Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogs

…, HW Moran, DA Shamblee, IM Uwaydah… - Journal of medicinal …, 1984 - ACS Publications
A series of substituted derivatives of 2-amino-3-benzoylphenylacetic acid (amfenac) has been
synthesized andevaluated for antiinflammatory, analgesic, and cyclooxygenase inhibiting …

Optically pure (+)-nicotine from (.+-.)-nicotine and biological comparisons with (-)-nicotine

MD Aceto, BR Martin, IM Uwaydah… - Journal of medicinal …, 1979 - ACS Publications
… Because of the growing implications regarding nicotine receptors, we decided to demonstrate
an important criterion, namely, pharmacological stereospecificity of these optically pure …

Evaluation of a suspension system for intravenous self-administration studies of water-insoluble compounds in the rhesus monkey

JM Carney, IM Uwaydah, RL Balster - Pharmacology Biochemistry and …, 1977 - Elsevier
IM injections were given 5 min before the start of the session. Sessions occurred daily
and drug injections were given every fifth day. Saline or emulphor vehicle injections were …

Structure-activity relationships of natural and synthetic cannabinoids in suppression of humoral and cell-mediated immunity.

SH Smith, LS Harris, IM Uwaydah, AE Munson - Journal of Pharmacology …, 1978 - ASPET
Delta-9-Tetrahydrocannabinol (delta-9-THC) a psychoactive constituent of marihuana, has
been shown in previous studies to suppress humoral and cell-mediated immunity. The …

Synthesis and pharmacological activity of some N-alkyl-substituted 9. alpha.-ethyl-2'-hydroxy-5-methyl-6, 7-benzomorphans

IM Uwaydah, EL May, LS Harris - Journal of Medicinal Chemistry, 1977 - ACS Publications
A series of N-substituted 9a-ethyl-2'-hydroxy-5-niethyl-6, 7-benzomorphans was synthesized
and evaluated for their narcotic analgesic and antagonistic activities. Compounds 2a and …

N-(2-Cyanoethyl) derivatives of meperidine, ketobemidone, and a potent 6, 7-benzomorphan

IM Uwaydah, MK Waddle… - Journal of Medicinal …, 1979 - ACS Publications
The IV-(2-cyanoethyl)-9a-ethyl-5-methyl-6, 7-benzomorphan (lc) is a more potent antinociceptive
and has stronger receptor binding affinity than its IV-methyl analogue lb. The IV-(2-…

STUDIES ON BETA-ADRENERGIC BLOCKING AGENTS: PART I. SYNTHETIC APPROACHES TO 2-HYDROXY-1, 6-METHANO (10) ANNULENE. PART II …

IM UWAYDAH - 1974 - search.proquest.com
have been used, the quality is heavily dependent upon the quality of the original Page 1 |NFORMATION
TO USERS This material was produced from a microfilm copy of the original …

Intramuscular versus intraosseous delivery of nerve agent antidote pralidoxime chloride in Swine

NI Uwaydah, SL Hoskins, SP Bruttig… - Prehospital …, 2016 - Taylor & Francis
… standard intramuscular (IM) injections. We compared the pharmacokinetics of IM and IO …
Ten normovolemic swine were randomly administered 2 mL, 660 mg 2-PAM Cl via the IM or …

Fungemia Caused by Candida Species and Torulopsis glabrata in the Hospitalized Patient: Frequency, Characteristics, and Evaluation of Factors Influencing …

SV Komshian, AK Uwaydah, JD Sobel… - Reviews of infectious …, 1989 - academic.oup.com
We reviewed 135 cases of candidemia occurring between 1983and 1986to examine oncologic
and nononcologic populations and assess factors for survival. Candida albieans was the …

[CITATION][C] Ab initio and semi-empirical molecular orbital calculations on 1, 6-methano [10] annulene

GL Grunewald, IM Uwaydah, RE Christoffersen… - Tetrahedron …, 1975 - Elsevier
U and blu to the highest bonding orbitale. Considering the documented ability of the molecular
fragment method to predict the electronic structure of molecules such as t. hese, 2 and the …