Microglia perform both neuroprotective and neurotoxic functions in the brain, with this
depending on their state of activation and their release of mediators. Upon P2X 7 receptor …

Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant neurodegenerative
disease characterized by various symptoms including cerebellar ataxia. Recently, several …

In our study, evidence is provided that strychnine, a competitive antagonist at glycine-gated
Cl − channels, is also a potent competitive antagonist at native α-7-containing, α-…

The effects of amantadine on nicotinic acetylcholine receptors (nAChRs) of hippocampal
neurons were studied by recording three types of acetylcholine (ACh)-evoked currents, using …

It has been shown that centrally administered neuropeptide Y (NPY) delays gastric emptying.
To determine the receptor subtypes of NPY mediating the inhibitory effects on gastric …

Tremor rat (tm/tm), the parent strain of spontaneously epileptic rat (SER: zi/zi, tm/tm), exhibits
absence-like seizures characterized by 5–7 Hz spike-wave-like complexes on cortical and …

Protein kinase C (PKC) is translocated to various cellular regions in a subtype and
stimulation‐dependent manner. Thereafter, the activated PKC phosphorylates its substrate and …

The receptor subtypes, which mediate nicotine-induced excitation of dopaminergic neurons
in the substantia nigra, were investigated by whole-cell patch clamp studies and single-cell …

Evidence is provided that rapid application of nicotinic agonists to CA1 interneurons in
hippocampal slices can trigger responses with at least one of three components: (i) whole-cell …

Purpose: The spontaneously epileptic rat (SER: tm/tm, zi/zi) shows both absence‐like seizures
and tonic convulsions. Our previous electrophysiologic studies have demonstrated that …