Cyanide-induced apoptosis of dopaminergic cells is promoted by BNIP3 and Bax modulation of endoplasmic reticulum-mitochondrial Ca2+ levels

L Zhang, L Li, HW Leavesley, X Zhang… - … of Pharmacology and …, 2010 - ASPET
Cyanide is a potent neurotoxicant that can produce dopaminergic neuronal death in the
substantia nigra and is associated with a Parkinson-like syndrome. In this study involvement of …

Interaction of cyanide and nitric oxide with cytochrome c oxidase: implications for acute cyanide toxicity

HB Leavesley, L Li, K Prabhakaran… - Toxicological …, 2008 - academic.oup.com
Acute cyanide toxicity is attributed to inhibition of cytochrome c oxidase (CcOX), the oxygen-reducing
component of mitochondrial electron transport; however, the mitochondrial action …

Nitrite-mediated antagonism of cyanide inhibition of cytochrome c oxidase in dopamine neurons

HB Leavesley, L Li, S Mukhopadhyay… - Toxicological …, 2010 - academic.oup.com
Cyanide inhibits aerobic metabolism by binding to the binuclear heme center of cytochrome
c oxidase (CcOX). Amyl nitrite and sodium nitrite (NaNO 2 ) antagonize cyanide toxicity in …

The role of nitric oxide in the cyanide-mediated inhibition of cytochrome c oxidase

HB Leavesley - 2009 - search.proquest.com
Cyanide causes rapid-onset neurotoxicity by inhibiting cellular respiration at cytochrome c
oxidase (CcOX). Cyanide primarily targets the brain, where it promotes dopaminergic cell …

Design and implementation of a calibrated hyperspectral small-animal imager: Practical and theoretical aspects of system optimization

SJ Leavesley - 2008 - search.proquest.com
… Silas Leavesley … Silas Leavesley … o My wife, Heather, for her support and advice, for
working to keep me cool and level-headed, and for encouraging me to make the right choices. …

Head of bed elevation in pediatric patients with severe traumatic brain injury

…, B Zhang, PB Storm, GG Heuer, L Leavesley… - Journal of …, 2020 - thejns.org
OBJECTIVE Head of bed (HOB) elevation to 30 after severe traumatic brain injury (TBI) has
become standard positioning across all age groups. This maneuver is thought to minimize …

Kewibu, Vincent

M Leavesley - Encyclopedia of Global Archaeology, 2020 - Springer
Kakadu National Park, located in the top end of the Northern Territory of Australia, covers
19,804 km2 of diverse tropical ecosystems. This vast area includes mangroves, mudflats and …

How long have dogs been in Melanesia? New evidence from Caution Bay, south coast of Papua New Guinea

T Manne, B David, F Petchey, M Leavesley… - Journal of …, 2020 - Elsevier
… The excavations at Moiapu 1 were directed by Matthew Leavesley with field excavation
team of Kerry Andrew, Nick Araho, Avis Babalu, Letizia Boin, Kirsten Bradley, Jason Kariwiga, …

[HTML][HTML] Using phylogenetically-informed annotation (PIA) to search for light-interacting genes in transcriptomes from non-model organisms

DI Speiser, MS Pankey, AK Zaharoff, BA Battelle… - BMC …, 2014 - Springer
Background Tools for high throughput sequencing and de novo assembly make the analysis
of transcriptomes (ie the suite of genes expressed in a tissue) feasible for almost any …

[HTML][HTML] Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats

…, YY Maxuitenko, N Li, WM Lowe, JD Whitt, W Zhang… - Cancers, 2023 - mdpi.com
Simple Summary This study describes a new compound, sulindac sulfide amide (SSA), which
is a derivative of the nonsteroidal anti-inflammatory drug (NSAID) sulindac. NSAIDs like …