IMP dehydrogenase, an enzyme linked with proliferation and malignancy
RC Jackson, G Weber, HP MORRIS - Nature, 1975 - nature.com
PREVIOUS studies conducted in this laboratory demonstrated that in a spectrum of liver
tumours with different growth rates there is an imbalance in the activities of key enzymes and …
tumours with different growth rates there is an imbalance in the activities of key enzymes and …
Ribonucleotide reductase and cell proliferation: I. Variations of ribonucleotide reductase activity with tumor growth rate in a series of rat hepatomas
HL Elford, M Freese, E Passamani, HP Morris - Journal of Biological …, 1970 - ASBMB
The relationship between ribonucleotide reductase and tumor growth rate was measured in
a series of rat hepatomas of different growth rates. An excellent correlation was found …
a series of rat hepatomas of different growth rates. An excellent correlation was found …
Increased CTP synthetase activity in cancer cells
JC Williams, H Kizaki, G Weber, HP Morris - Nature, 1978 - nature.com
AN insight into the biochemical strategy of cancer cells has been achieved by the conceptual
and experimental approach provided by the molecular correlation concept 1,2 . Studies …
and experimental approach provided by the molecular correlation concept 1,2 . Studies …
Superoxide dismutase and superoxide radical in Morris hepatomas
IB Bize, LW Oberley, HP Morris - Cancer Research, 1980 - AACR
Total superoxide dismutase (SOD) and manganese superoxide dismutase (Mn SOD) specific
activities were measured in tissue homogenates and in isolated mitochondria from normal …
activities were measured in tissue homogenates and in isolated mitochondria from normal …
Increased cytidine 5′-triphosphate synthetase activity in rat and human tumors
H Kizaki, JC Williams, HP Morris, G Weber - Cancer research, 1980 - AACR
The behavior of the activity of the rate-limiting enzyme of cytidine 5′-triphosphate (CTP)
biosynthesis, CTP synthetase (EC 6.3.4.2), was elucidated in the rat in normal liver, in 14 …
biosynthesis, CTP synthetase (EC 6.3.4.2), was elucidated in the rat in normal liver, in 14 …
Comparative biochemistry of hepatomas: III. Carbohydrate enzymes in liver tumors of different growth rates
G Weber, HP Morris - Cancer Research, 1963 - AACR
The behavior of carbohydrate enzymes was examined in a spectrum of hepatomas of different
growth rates, and results were evaluated in the light of data obtained in Hepatoma 5123-D …
growth rates, and results were evaluated in the light of data obtained in Hepatoma 5123-D …
Comparative biochemistry of hepatomas: IV. Isotope studies of glucose and fructose metabolism in liver tumors of different growth rates
MJ Sweeney, J Ashmore, HP Morris, G Weber - Cancer Research, 1963 - AACR
The metabolic fate of labeled fructose and glucose was compared in normal liver and in
hepatomas of different growth rates. For certain biochemical parameters a rough correlation with …
hepatomas of different growth rates. For certain biochemical parameters a rough correlation with …
Glutaminase activities and growth rates of rat hepatomas
M Linder-Horowitz, WE Knox, HP Morris - Cancer research, 1969 - AACR
For a series of transplantable rat hepatomas, the growth rate, as well as the type and quantity
of glutaminase activity, was determined. The times for volume doubling of the hepatomas …
of glutaminase activity, was determined. The times for volume doubling of the hepatomas …
Behavior of transaldolase (EC 2.2. 1.2) and transketolase (EC 2.2. 1.1) activities in normal, neoplastic, differentiating, and regenerating liver
PC Heinrich, HP Morris, G Weber - Cancer Research, 1976 - AACR
The objective of this investigation was to throw light on the biological behavior and metabolic
regulation of hepatic enzymes of the nonoxidative branch of the pentose phosphate …
regulation of hepatic enzymes of the nonoxidative branch of the pentose phosphate …
Comparative biochemistry of hepatomas I. Carbohydrate enzymes in Morris hepatoma 5123
G Weber, G Banerjee, HP Morris - Cancer Research, 1961 - AACR
A systematic study of the carbohydrate-metabolizing enzyme systems of the Morris hepatoma
5123 was carried out, and results were interpreted in the light of normal liver data and in …
5123 was carried out, and results were interpreted in the light of normal liver data and in …