Dorsal horn gastrin-releasing peptide receptor (GRPR) neurons have a central role in itch
transmission. Itch signaling has been suggested to be controlled by an inhibitory network in …

Itch stimuli are detected by specialized primary afferents that convey the signal to the spinal
cord, but how itch transmission is regulated is still not completely known. Here, we …

Background The glycinergic system plays an important inhibitory role in the mouse central
nervous system, where glycine controls the excitability of spinal itch- and pain-mediating …

Glycinergic neurons regulate nociceptive and pruriceptive signaling in the spinal cord, and
the identity and role of the glycine-regulated neurons are not fully known. Herein, we have …

Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1929. 95
pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1768-7. Spinal glycinergic …

Rodent primary somatosensory cortex (S1) is organized in defined layers, where layer IV
serves as the main target for thalamocortical projections. Serotoninergic signaling is important …

Glycinergic neurons regulate nociceptive and pruriceptive signaling in the spinal cord, but
the identity and role of the glycine-regulated neurons are not fully known. Herein, we have …

Urocortin 3 (UCN3) is a neuropeptide involved in mechanosensation and stress regulation,
and Ucn3-Cre neurons have been assigned a role in mechanical itch. Here, we show that …

The glycinergic system serves a protective role in acute itch and pain transmission and further,
in inflammatory-and nerve damage-induced hypersensitivity. The glycine receptor alpha …

Pain and itch are two distinct sensations, but the fundamental question of how our nervous
system distinguishes the processing and encoding of their related information is still far to be …