The effects of insulin-like growth factors on tumorigenesis and neoplastic growth

HM Khandwala, IE McCutcheon, A Flyvbjerg… - Endocrine …, 2000 - academic.oup.com
… Using [ 3 H]thymidine incorporation as a tumor growth marker, they reported that 9/10 glioma
cell lines responded to IGF-I with increases in[ 3 H]thymidine incorporation that ranged from …

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial

…, V Pichette, G Nesrallah, HS Bajaj, H Khandwala… - The Lancet, 2019 - thelancet.com
Background Short-term treatment for people with type 2 diabetes using a low dose of the
selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing …

Low serum alkaline phosphatase activity and pathologic fracture: case report and brief review of hypophosphatasia diagnosed in adulthood

HM Khandwala, S Mumm, MP Whyte - Endocrine Practice, 2006 - Elsevier
Objective To describe an elderly patient with low serum alkaline phosphatase (ALP) activity
detected after a pathologic fracture and to characterize hypophosphatasia in adult patients. …

Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus

H Wang, QH Meng, JR Gordon, H Khandwala, L Wu - Clinical biochemistry, 2007 - Elsevier
OBJECTIVE:: To determine the effect of methylglyoxal (MG) on cytokine production by, and
apoptosis of, neutrophils from type 2 diabetes mellitus (T2DM) patients. DESIGN AND …

The growth of a shadow banking system in emerging markets: Evidence from India

VV Acharya, H Khandwala, TS Öncü - Journal of International Money and …, 2013 - Elsevier
We study the determinants of the growth of those non-deposit taking non-bank financial
corporations (NBFCs) which are regarded by the Reserve Bank of India as being systemically …

IMpact of flash glucose Monitoring in pEople with type 2 Diabetes Inadequately controlled with non‐insulin Antihyperglycaemic ThErapy (IMMEDIATE): A randomized …

…, L Chu, HS Bajaj, H Khandwala… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To examine the efficacy and patient satisfaction of intermittently scanned continuous
glucose monitoring (isCGM) in adults using non‐insulin therapies for the management of type 2 …

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial

…, B Ajala, A Jain, S Ross, H Bajaj, H Khandwala… - The Lancet, 2018 - thelancet.com
Background There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin,
a selective serotonin 2C receptor agonist that suppresses appetite, has been shown to …

[HTML][HTML] A pre-specified analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) randomized controlled trial on the …

…, A Dowell, M Langlois, N Muirhead, H Khandwala… - Kidney international, 2022 - Elsevier
This pre-specified analysis of DAPA-CKD assessed the impact of sodium-glucose cotransporter
2 inhibition on abrupt declines in kidney function in high-risk patients based on having …

Lowest glucose variability and hypoglycemia are observed with the combination of a GLP-1 receptor agonist and basal insulin (VARIATION Study)

…, K Venn, C Ye, A Patrick, S Kalra, H Khandwala… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE There is a dearth of published literature comparing glucose variability (GV)
between different insulin regimens in type 2 diabetes. This cohort study compares GV using …

Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis

CW Loomis, H Khandwala, G Osmond… - Journal of Pharmacology …, 2001 - ASPET
… Preliminary time course studies indicated that a 15-min pretreatment time was optimal for
it drug administration and that 1.5 h between doses was sufficient for complete recovery from …