Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are
profoundly diminished and prone to apoptotic deletion. In this study, we investigate whether …

The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and
induces their apoptotic deletion or functional inactivation. We investigated whether galectin-9/…

Optimal immune activation of naïve CD8 T cells requires signal 1 mediated by the T cell
receptor, signal 2 mediated by co-stimulation and signal 3 provided by pro-inflammatory …

Hepatocellular carcinoma (HCC) often develops following chronic hepatitis B virus (HBV)
infection and responds poorly to immune checkpoint blockade. Here, we examined the antigen …

To address complications of pathogenic antibody or life-threatening anaphylactic reactions
in protein replacement therapy for patients with hemophilia or other inherited protein …

HIV-Tat protein has been implicated in the pathogenesis of HIV-1 neurological complications
(ie, neuroAIDS), but direct demonstrations of the effects of Tat on behavior are limited. GT-…

The mode of n‐hexadecane uptake by two organisms—Pseudomonas M 1 and Pseudomonas
N 1—was studied. During the growth of Pseudomonas M 1 on n‐hexadecane, no …

Grains from seven common pulses grown in India were separated into seed coat, cotyledons,
endosperm (in guar only), and embryo, and the proportion of each was determined. All …

Despite its medical applications, the mechanisms responsible for the osseointegration of
bioactive glass (45S5) have yet to be fully understood. Evidence suggests that the strongest …

Venous thromboembolism (VTE), the third leading cardiovascular complication, requires
more understanding at molecular levels. Here, we have identified miR-145 as a key molecule …