[HTML][HTML] ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer

P Zou, J Zhang, Y Xia, K Kanchana, G Guo, W Chen… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric cancer is one of the leading causes of cancer mortality in the world, and finding
novel agents and strategies for the treatment of advanced gastric cancer is of urgent need. …

Prediction of central compartment lymph node metastasis in papillary thyroid microcarcinoma

…, Z Chen, J Jiang, Y Chen, L Jin, G Guo… - Clinical …, 2014 - Wiley Online Library
Objectives We aimed to determine the predictive factors for central compartment lymph node
metastasis ( LNM ) in papillary thyroid microcarcinoma ( PTMC ). Design and patients We …

[HTML][HTML] Osthole inhibits triple negative breast cancer cells by suppressing STAT3

X Dai, C Yin, Y Zhang, G Guo, C Zhao, O Wang… - Journal of Experimental …, 2018 - Springer
Background Triple-negative breast cancer (TNBC) is an aggressive subgroup of human
breast cancer. Patients with TNBC have poor clinical outcome as they are non-responsive to …

Curcumin analog L48H37 prevents lipopolysaccharide-induced TLR4 signaling pathway activation and sepsis via targeting MD2

…, G Chen, Y Zhang, Z Wang, L Dong, J Wu, G Guo… - … of Pharmacology and …, 2015 - ASPET
Endotoxin-induced acute inflammatory diseases such as sepsis, mediated by excessive
production of various proinflammatory cytokines, remain the leading cause of mortality in …

[HTML][HTML] Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway

…, S Xu, Z Liu, T Yan, G Liang, G Guo… - Biomedicine & …, 2019 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer lacking prognostic and
effective therapeutic targets currently. In this study, we evaluated the toxic potential of …

Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3

X Dai, C Yin, G Guo, Y Zhang, C Zhao, J Qian… - Toxicology and applied …, 2018 - Elsevier
Triple negative breast cancer (TNBC) is an aggressive subgroup of human breast cancer. In
this study, we have examined the potential of Schisandrin B (Sch B), a bioactive chemical …

Clinical significance of miR-21 expression in breast cancer: SYBR-Green I-based real-time RT-PCR study of invasive ductal carcinoma

GL Huang, XH Zhang, GL Guo… - Oncology …, 2009 - spandidos-publications.com
Growing evidence suggests microRNAs (miRNAs) have an important role in tumorigenesis.
MicroRNA-21 (miR-21) is up-regulated in many malignant tumors, including breast cancer. …

LncRNA PRKCQ‐AS1 regulates paclitaxel resistance in triple‐negative breast cancer cells through miR‐361‐5p/PIK3C3 mediated autophagy

…, J Zhou, K Lu, J Gu, R Ma, G Guo - Clinical and …, 2023 - Wiley Online Library
Paclitaxel (PTX) resistance is a key cause of chemotherapy failure in patients with triple
negative breast cancer (TNBC). The aim of this study is to investigate the effect and mechanism …

[HTML][HTML] (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1

X Dai, G Guo, P Zou, R Cui, W Chen, X Chen… - Journal of Experimental …, 2017 - Springer
Background Non–small cell lung cancer (NSCLC) accounts for approximately 80–85% of all
lung cancers and is usually diagnosed at an advanced stage with poor prognosis. Targeted …

[HTML][HTML] Coexpression of VEGF-C and COX-2 and its association with lymphangiogenesis in human breast cancer

XH Zhang, DP Huang, GL Guo, GR Chen, HX Zhang… - BMC cancer, 2008 - Springer
Background Lymphangiogenesis has become a new research frontier in tumor metastasis
since the discovery of reliable lymphatic markers that have allowed observation and isolation …