Down-regulation of rat hepatic microsomal cytochromes P-450 in microvesicular steatosis induced by orotic acid
GM Su, RM Sefton, M Murray - Journal of Pharmacology and Experimental …, 1999 - ASPET
Microvesicular steatosis is an important component of the overall pathogenesis of drug-mediated
liver injury. Although mitochondrial damage has a role in the development of …
liver injury. Although mitochondrial damage has a role in the development of …
Effect of alcohol on cytochrome p450 arachidonic acid metabolism and blood pressure in rats and its modulation by red wine polyphenolics
C Cowpland, GM Su, M Murray… - Clinical and …, 2006 - Wiley Online Library
… Gloria M Su … Gloria M Su … The instrument was run in selected ion monitoring mode and
ions m/z 391 and m/z 393 (d 2 -internal standard), representing loss of pentafluorobenzyl radical …
ions m/z 391 and m/z 393 (d 2 -internal standard), representing loss of pentafluorobenzyl radical …
The potential of N-[2-(dimethylamino) ethyl] acridine-4-carboxamide] to circumvent three multidrug-resistance phenotypes in vitro
RA Davey, GM Su, RM Hargrave, RM Harvie… - Cancer chemotherapy …, 1997 - Springer
The effectiveness of N-[2-(dimethylamino) ethyl]acridine-4-carboxamide (DACA) relative to
that of amsacrine, idarubicin, daunorubicin and paclitaxel against three different forms of …
that of amsacrine, idarubicin, daunorubicin and paclitaxel against three different forms of …
Pretranslational upregulation of microsomal CYP4A in rat liver by intake of a high-sucrose, lipid-devoid diet containing orotic acid
GM Su, E Fiala-Beer, J Weber, D Jahn… - Biochemical …, 2005 - Elsevier
In rodents, high-fat diets promote hepatic lipid accumulation in rodents, activation of peroxisome
proliferator activated receptor-α (PPARα) and upregulation of cytochrome P450 (CYP) …
proliferator activated receptor-α (PPARα) and upregulation of cytochrome P450 (CYP) …
[HTML][HTML] Phospho-STAT5 accumulation in nuclear fractions from vitamin A-deficient rat liver
M Murray, AM Butler, E Fiala-Beer, GM Su - FEBS letters, 2005 - Elsevier
The growth hormone (GH)-responsive cytochrome P450 (CYP) 2C11 is down-regulated in
vitamin A-deficient (VAD) rat liver. This study assessed the impact of a VAD diet on the …
vitamin A-deficient (VAD) rat liver. This study assessed the impact of a VAD diet on the …
Generic GPCR residue numbers–aligning topology maps while minding the gaps
Generic residue numbers facilitate comparisons of, for example, mutational effects, ligand
interactions, and structural motifs. The numbering scheme by Ballesteros and Weinstein for …
interactions, and structural motifs. The numbering scheme by Ballesteros and Weinstein for …
[HTML][HTML] Bioactive amines in soy sauce: Validation of method, occurrence and potential health effects
LR Guidi, MBA Gloria - Food Chemistry, 2012 - Elsevier
The objective of this study was to investigate the levels of bioactive amines in soy sauce. A
method for the extraction of amines was optimized and an ion pair-HPLC method was …
method for the extraction of amines was optimized and an ion pair-HPLC method was …
Cadmium, copper and lead levels in different cultivars of lettuce and soil from urban agriculture
…, EAN Knupp, HEL Palmieri, JBB Silva, MBA Glória - Environmental …, 2018 - Elsevier
Urban agriculture plays an important role in sustainable food supply. However, because of
the atmospheric pollution and soil contamination associated with urban areas, this activity …
the atmospheric pollution and soil contamination associated with urban areas, this activity …
[PDF][PDF] 5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology
Drugs frequently require interactions with multiple targets—via a process known as
polypharmacology—to achieve their therapeutic actions. Currently, drugs targeting several serotonin …
polypharmacology—to achieve their therapeutic actions. Currently, drugs targeting several serotonin …
[PDF][PDF] Pharmacogenomics of GPCR drug targets
Natural genetic variation in the human genome is a cause of individual differences in
responses to medications and is an underappreciated burden on public health. Although 108 G-…
responses to medications and is an underappreciated burden on public health. Although 108 G-…