Hippocampal long-term potentiation (LTP) is a remarkably stable facilitation of synaptic
responses resulting from very brief trains of high-frequency stimulation 1,2 . Because of its …

Recent studies have uncovered a synaptic process with properties required for an
intermediate step in memory storage. Calcium rapidly and irreversibly increases the number of …

Short, high frequency stimulation bursts (4 pulses at 100 Hz) were applied to Schaffer/commissural
projections to the CA1 field of rat hippocampal slices at 0.1, 0.2, 1.0 or 2.0-s intervals …

This study investigated whether positive modulators of AMPA-type glutamate receptors
influence neurotrophin expression by forebrain neurons. Treatments with the ampakine CX614 …

Recent work has shown that the hippocampus contains a class of receptors for the excitatory
amino acid glutamate that are activated by N-methyl-D-aspartate (NMDA) 1 and that exhibit …

BRIEF trains of electrical stimulation delivered to any one of several hippocampal pathways
often result in immediate and long-lasting enhancement of subsequent postsynaptic …

Electrical stimulation of axons in the hippocampus with short high-frequency bursts that
resemble in vivo activity patterns produces stable potentiation of postsynaptic responses when …

1. The consequences of repetitive activation of excitatory synaptic inputs to the CA1 pyramidal
cells of rat hippocampus have been studied using in vitro techniques. 2. Single stimulation …

Progressive cognitive deficits that emerge with aging are a result of complex interactions of
genetic and environmental factors. Whereas much has been learned about the genetic …

The contributions of two subclasses of excitatory amino acid transmitter receptors to the
induction and expression of long-term potentiation (LTP) were analyzed in hippocampal slices. …