User profiles for G. L. Johnson

Gary l Johnson

University of North Carolina School of Medicine
Verified email at med.unc.edu
Cited by 57153

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

GL Johnson, R Lapadat - Science, 2002 - science.org
Multicellular organisms have three well-characterized subfamilies of mitogen-activated protein
kinases (MAPKs) that control a vast array of physiological processes. These enzymes are …

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

…, S Gibson, MB Jarpe, GL Johnson - Physiological …, 1999 - journals.physiology.org
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-Activated
Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human. Physiol…

Organization and regulation of mitogen-activated protein kinase signaling pathways

TP Garrington, GL Johnson - Current opinion in cell biology, 1999 - Elsevier
Mitogen-activated protein kinases (MAPKs) are components of a three kinase regulatory
cascade. There are multiple members of each component family of kinases in the MAPK module…

A knowledge-based approach to the statistical mapping of climate

C Daly, WP Gibson, GH Taylor, GL Johnson… - Climate research, 2002 - int-res.com
The demand for spatial climate data in digital form has risen dramatically in recent years. In
response to this need, a variety of statistical techniques have been used to facilitate the …

[BOOK][B] Wind energy systems

GL Johnson - 1985 - Citeseer
Look at the ships also:, though they are so great and are driven by strong winds, they are
guided by a very small rudder wherever the will of the pilot directs. James 3: 4 The wind is a free…

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

…, C Lange-Carter, B Dérijard, RJ Davis, GL Johnson… - Science, 1994 - science.org
INK Mitogen-Activated Protein Kinases by Raf-1 and MEKK Page 1 I * pacity of these
proteins resulted in a decreased amount of translation of the psbA mRNA, we analyzed the …

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

…, CM Pleiman, AM Gardner, KJ Blumer, GL Johnson - Science, 1993 - science.org
Mitogen-activated protein kinases (MAPKs) are rapidly phosphorylated and activated in
response to various extracellular stimuli in many different cell types. Such regulation of MAPK …

Coordination of Rho GTPase activities during cell protrusion

…, H Elliott, O Pertz, P Nalbant, A Abell, GL Johnson… - Nature, 2009 - nature.com
The GTPases Rac1, RhoA and Cdc42 act together to control cytoskeleton dynamics 1 , 2 , 3
. Recent biosensor studies have shown that all three GTPases are activated at the front of …

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

…, FX Claret, C Lange-Carter, F Mercurio, GL Johnson… - Science, 1995 - science.org
One Ras-dependent protein kinase cascade leading from growth factor receptors to the
ERK (extracellular signal-regulated kinases) subgroup of mitogen-activated protein kinases (…

[HTML][HTML] Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

…, J Jin, SV Frye, HS Earp, LM Graves, GL Johnson - Cell, 2012 - cell.com
Kinase inhibitors have limited success in cancer treatment because tumors circumvent their
action. Using a quantitative proteomics approach, we assessed kinome activity in response …