Amphiphilic block copolymers for drug delivery
… to polymers with a molecular weight >10,000 g/mol, whereas PEG is … g/mol) solutions have
been safely administered intravenously to rats, guinea pigs, rabbits, and monkeys up to 16 g/…
been safely administered intravenously to rats, guinea pigs, rabbits, and monkeys up to 16 g/…
Block copolymer micelles as long-circulating drug vehicles
… g/mol and a PAsp molecular weight of 2100 g/mol. The circulation time of PEO-PAsp-DOX
decreases as the molecular weight of the PAsp block increases, and there is a concurrent …
decreases as the molecular weight of the PAsp block increases, and there is a concurrent …
Polymeric micelles as new drug carriers
… At 24 h, levels of conjugate were about 10% dose/g tumor, whereas levels of free drug
were about 1% dose/g tumor. In addition, levels at the heart, site of cardiotoxicity of DOX, were …
were about 1% dose/g tumor. In addition, levels at the heart, site of cardiotoxicity of DOX, were …
[HTML][HTML] Hygro-responsive membranes for effective oil–water separation
… Here is the capillary length for the liquid, γ lv is the liquid surface tension, ρ is the liquid
density and g is the acceleration due to gravity. The reference pressure is approximately the …
density and g is the acceleration due to gravity. The reference pressure is approximately the …
Poly (ethylene oxide)-block-poly (L-amino acid) micelles for drug delivery
A Lavasanifar, J Samuel, GS Kwon - Advanced drug delivery reviews, 2002 - Elsevier
… The hydrophilic block in these systems is usually PEO with a molecular weight ranging
from 1000 to 20,000 g mol −1 . PEO has been used safely in humans and is approved by …
from 1000 to 20,000 g mol −1 . PEO has been used safely in humans and is approved by …
Towards tuberculosis elimination: an action framework for low-incidence countries
…, W Haas, A Järvinen, GY Kwon… - European …, 2015 - Eur Respiratory Soc
This paper describes an action framework for countries with low tuberculosis (TB) incidence
(<100 TB cases per million population) that are striving for TB elimination. The framework …
(<100 TB cases per million population) that are striving for TB elimination. The framework …
Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly (ethylene oxide-aspartate) block copolymer-adriamycin conjugates
Micelle-forming block copolymer-drug conjugates offer a new vehicle design for drug delivery
that may be useful for the targeting of tumors. We have investigated the biodistribution of …
that may be useful for the targeting of tumors. We have investigated the biodistribution of …
Organic batteries for a greener rechargeable world
… , resulting in capacities of approximately 503 mAh g −1 or 723 mAh g −1 and energy densities
of … limit of 270 mAh g −1 owing to their heavy transition-metal-element content 32,80,81 . …
of … limit of 270 mAh g −1 owing to their heavy transition-metal-element content 32,80,81 . …
Polymeric micelles for drug delivery
SR Croy, GS Kwon - Current pharmaceutical design, 2006 - ingentaconnect.com
… The total approximate mass of an intact micelle is typically on the order of 105 to 106 g/mol
[70, 113, 114]. The renal molecular weight threshold for clearance is a gradient, where …
[70, 113, 114]. The renal molecular weight threshold for clearance is a gradient, where …
Doxorubicin-loaded poly (ethylene glycol)–poly (β-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance
…, Y Sakurai, S Fukushima, K Okamoto, GS Kwon - Journal of Controlled …, 2000 - Elsevier
… A schedule of four bolus injections of 0.1 ml/10 g body weight with 3-day intervals was
adopted in this study. Physiological saline in the same volume and interval as the drug solution …
adopted in this study. Physiological saline in the same volume and interval as the drug solution …