Oral contraceptives: are drug interactions of clinical significance?
GM Shenfield - Drug Safety, 1993 - Springer
There is a large quantity of literature on drug interactions with oral contraceptive (OC)
steroids although their incidence is not known. The potential clinical significance of some …
steroids although their incidence is not known. The potential clinical significance of some …
[HTML][HTML] Genetic polymorphisms, drug metabolism and drug concentrations
GM Shenfield - The Clinical Biochemist Reviews, 2004 - ncbi.nlm.nih.gov
The interfaces between genetics and drug metabolism have recently been the subjects of
intense research activity. Pharmacogenomics uses molecular biological techniques to study …
intense research activity. Pharmacogenomics uses molecular biological techniques to study …
Drug combinations and impaired renal function–the 'triple whammy'
KK Loboz, GM Shenfield - British journal of clinical …, 2005 - Wiley Online Library
Background Recent studies have identified the ‘triple whammy’ in which combinations of
diuretics, nonsteroidal anti‐inflammatory drugs (NSAIDs), ACE inhibitors (ACEI) and/or …
diuretics, nonsteroidal anti‐inflammatory drugs (NSAIDs), ACE inhibitors (ACEI) and/or …
Influence of thyroid dysfunction on drug pharmacokinetics
GM Shenfield - Clinical Pharmacokinetics, 1981 - Springer
When thyroid function is altered there are a series of physiological changes which are likely
to affect drug absorption, metabolism or excretion, and altered pharmacokinetics have been …
to affect drug absorption, metabolism or excretion, and altered pharmacokinetics have been …
Functional ability of patients to manage medication packaging: a survey of geriatric inpatients
…, TP Finnegan, SJ Ogle, GM Shenfield - Age and ageing, 1994 - academic.oup.com
This study measured the prevalence of difficulty experienced by elderly inpatients in opening
and removing tablets from a range of common commercial medication packagings and in …
and removing tablets from a range of common commercial medication packagings and in …
Pregnancy attributable to interaction between tetracycline and oral contraceptives.
JF Bacon, GM Shenfield - British Medical Journal, 1980 - ncbi.nlm.nih.gov
Various drugs, including antibiotics, may cause failure of contraception and breakthrough
bleeding in patients on oral contraceptives.'Early reports implicated rifampicin,'which was later …
bleeding in patients on oral contraceptives.'Early reports implicated rifampicin,'which was later …
Optimizing the use of antithrombotic therapy for atrial fibrillation in older people: a pharmacist‐led multidisciplinary intervention
…, SJ Ogle, MJ Duguid, GM Shenfield - Journal of the …, 2005 - Wiley Online Library
Objectives: To develop, implement, and evaluate a pharmacist‐led multidisciplinary intervention
in a hospital setting that would optimize antithrombotic use in elderly atrial fibrillation …
in a hospital setting that would optimize antithrombotic use in elderly atrial fibrillation …
Adrenal suppression following extradural steroids
S Jacobs, PT Pullan, JM POTTER, GM Shenfield - Anaesthesia, 1983 - Wiley Online Library
Adrenocortical function was tested in 12 patients following a single lumbar extradural injection
ofmethyl‐prednisolone acetate (‘Depo‐Medrol’) 80 mg as treatment for chronic sciatica. …
ofmethyl‐prednisolone acetate (‘Depo‐Medrol’) 80 mg as treatment for chronic sciatica. …
Amelioration of experimental cisplatin and paclitaxel neuropathy with glutamate
FM Boyle, HR Wheeler, GM Shenfield - Journal of neuro-oncology, 1999 - Springer
A major toxic effect of the chemotherapeutic agents paclitaxel and cisplatin is peripheral
neuropathy. We report the use of a rat model of cytotoxic neuropathy to evaluate the role of …
neuropathy. We report the use of a rat model of cytotoxic neuropathy to evaluate the role of …
Health professionals rarely record history of complementary and alternative medicines
…, M Duguid, GM Shenfield - British Journal of Clinical …, 2005 - Wiley Online Library
Aims To identify the completeness of documentation of Complementary And Alternative
Medicine (CAM) use in hospital medical records of patients before and after an education …
Medicine (CAM) use in hospital medical records of patients before and after an education …