User profiles for G. K. Acquaah-Mensah
George K Acquaah MensahProfessor of Pharmaceutical Sciences, Massachusetts College of Pharmacy & Health … Verified email at mcphs.edu Cited by 2045 |
A tale of two diseases: Exploring mechanisms linking diabetes mellitus with Alzheimer's disease
…, C Ogunwale, GK Acquaah-Mensah - Journal of …, 2022 - content.iospress.com
Dementias, including the type associated with Alzheimer’s disease (AD), are on the rise
worldwide. Similarly, type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic …
worldwide. Similarly, type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic …
The compositional structure of Gene Ontology terms
PV Ogren, KB Cohen, GK Acquaah-Mensah… - Biocomputing …, 2003 - World Scientific
An analysis of the term names in the Gene Ontology reveals the prevalence of substring
relations between terms: 65.3% of all GO terms contain another GO term as a proper substring. …
relations between terms: 65.3% of all GO terms contain another GO term as a proper substring. …
Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium chabaudi-infected mice
…, MA Elfawal, MJ Towler, GK Acquaah-Mensah… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance The Chinese have used Artemisia annua as a tea infusion
to treat fever for >2000 years. The active component is artemisinin. Previously we showed …
to treat fever for >2000 years. The active component is artemisinin. Previously we showed …
[HTML][HTML] SAGA: a hybrid search algorithm for Bayesian Network structure learning of transcriptional regulatory networks
Bayesian Networks have been used for the inference of transcriptional regulatory relationships
among genes, and are valuable for obtaining biological insights. However, finding …
among genes, and are valuable for obtaining biological insights. However, finding …
A regulatory role for the insulin-and BDNF-linked RORA in the hippocampus: implications for Alzheimer's disease
GK Acquaah-Mensah, N Agu, T Khan… - Journal of Alzheimer's …, 2015 - content.iospress.com
Alzheimer's disease (AD) is the leading cause of dementia. The etiology of AD remains, in
large part, unresolved. In this study, gene expression (microarray) data from postmortem …
large part, unresolved. In this study, gene expression (microarray) data from postmortem …
Restricted-derestricted dynamic Bayesian network inference of transcriptional regulatory relationships among genes in cancer
ES Adabor, GK Acquaah-Mensah - Computational biology and chemistry, 2019 - Elsevier
Understanding transcriptional regulatory relationships among genes is important for gaining
etiological insights into diseases such as cancer. To this end, high-throughput biological …
etiological insights into diseases such as cancer. To this end, high-throughput biological …
Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells
Fludarabine is used to treat chronic lymphocytic leukemia. Both in vitro and in vivo studies
have indicated that apoptosis is an important mode of fludarabine-induced cell death. …
have indicated that apoptosis is an important mode of fludarabine-induced cell death. …
[HTML][HTML] Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease
GK Acquaah-Mensah, D Malhotra… - PLoS computational …, 2012 - journals.plos.org
Chronic obstructive pulmonary disease (COPD) is a major global health problem. The
etiology of COPD has been associated with apoptosis, oxidative stress, and inflammation. …
etiology of COPD has been associated with apoptosis, oxidative stress, and inflammation. …
Multi-omics inference of differential breast cancer-related transcriptional regulatory network gene hubs between young Black and White patients
B Aguilar, K Abdilleh, GK Acquaah-Mensah - Cancer Genetics, 2023 - Elsevier
Objective Breast cancers (BrCA) are a leading cause of illness and mortality worldwide. Black
women have a higher incidence rate relative to white women prior to age 40 years, and a …
women have a higher incidence rate relative to white women prior to age 40 years, and a …
Brain in situ hybridization maps as a source for reverse-engineering transcriptional regulatory networks: Alzheimer's disease insights
GK Acquaah-Mensah, RC Taylor - Gene, 2016 - Elsevier
Microarray data have been a valuable resource for identifying transcriptional regulatory
relationships among genes. As an example, brain region-specific transcriptional regulatory …
relationships among genes. As an example, brain region-specific transcriptional regulatory …