[PDF][PDF] Nonalcoholic fatty liver disease: from steatosis to cirrhosis

GC Farrell, CZ Larter - Hepatology, 2006 - Wiley Online Library
… McCuskey R, Ito Y, Robertson GR, McCuskey MK, Perry M, Farrell GC. Hepatic microvascular
dysfunction during evolution of dietary steatohepatitis in mice. HEPATOLOGY 2004;40:386…

[HTML][HTML] Epidemiology of non-alcoholic fatty liver disease in China

JG Fan, GC Farrell - Journal of hepatology, 2009 - Elsevier
Fatty liver (steatosis) is highly prevalent in China and is more often linked to obesity than to
alcoholism. Among more affluent regions of China, the community prevalence of non-…

Etiopathogenesis of nonalcoholic steatohepatitis

S Chitturi, GC Farrell - Seminars in liver disease, 2001 - thieme-connect.com
The definable causes of nonalcoholic steatohepatitis (NASH) include jejunoileal bypass
surgery (JIB), other causes of rapid and profound weight loss in obese subjects, total parenteral …

[PDF][PDF] The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD

…, G Marchesini, E Bugianesi, J George, GC Farrell… - …, 2007 - Wiley Online Library
Patients with nonalcoholic fatty liver disease (NAFLD) and advanced liver fibrosis are at the
highest risk for progressing to end‐stage liver disease. We constructed and validated a …

NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome

S Chitturi, S Abeygunasekera, GC Farrell… - Hepatology, 2002 - Elsevier
Nonalcoholic steatohepatitis (NASH) is often linked with disorders that are clearly associated
with insulin resistance (IR): obesity, type 2 diabetes mellitus, and hypertriglyceridemia. We …

[PDF][PDF] Beyond insulin resistance in NASH: TNF‐α or adiponectin?

JM Hui, A Hodge, GC Farrell, JG Kench, A Kriketos… - …, 2004 - Wiley Online Library
Farrell GC. Non-alcoholic steatohepatitis: what is it, and why is it important in the Asia-…
Hui JM, Farrell GC. Clear messages from sonographic shadows? Links between metabolic …

Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression

JM Hui, A Sud, GC Farrell, P Bandara, K Byth… - Gastroenterology, 2003 - Elsevier
Background & Aims : Chronic hepatitis C virus infection is associated with an increased
prevalence of type 2 diabetes. We hypothesized that virus-induced insulin resistance may be a …

[HTML][HTML] CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

IA Leclercq, GC Farrell, J Field, DR Bell… - The Journal of …, 2000 - Am Soc Clin Investig
Nonalcoholic steatohepatitis (NASH) and alcoholic liver disease have similar pathological
features. Because CYP2E1 plays a key role in alcoholic liver disease with its ability to …

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

…, K Schroder, MA Cooper, AE Feldstein, GC Farrell - Journal of …, 2017 - Elsevier
Background & Aims NOD-like receptor protein 3 (NLRP3) inflammasome activation occurs in
Non-alcoholic fatty liver disease (NAFLD). We used the first small molecule NLRP3 inhibitor…

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

MD Weltman, GC Farrell, P Hall… - Hepatology, 1998 - journals.lww.com
… George J, Murray M, Byth K, Farrell GC. Differential alterations of cytochrome P450
proteins in livers from patients with severe chronic liver disease. HEPATOLOGY 1995;21:120-128. …