Antitumor 1-(X-aryl)-3, 3-dialkyltriazenes. 1. Quantitative structure-activity relationships vs L1210 leukemia in mice

GJ Hatheway, C Hansch, KH Kim… - Journal of medicinal …, 1978 - ACS Publications
Quantitative structure-activity relationships (QSAR) have been formulated for phenyl-,
pyrazolyl-, and imida-zolyltriazenes acting against L1210 leukemia in mice. All three sets of …

Ames test of 1-(X-phenyl)-3, 3-dialkyltriazenes. A quantitative structure-activity study

BH Venger, C Hansch, GJ Hatheway… - Journal of Medicinal …, 1979 - ACS Publications
The mutagenicity of l-(X-phenyl)-3, 3-dialkyltriazenes was tested in the Ames test using
Salmonella typhimurium TA92. The following quantitative structure-activity relationship (QSAR) …

Pharmacokinetics of cefonicid, a new broad-spectrum cephalosporin

SL Barriere, GJ Hatheway… - Antimicrobial Agents …, 1982 - Am Soc Microbiol
This study determined the pharmacokinetic disposition of cefonicid. A single dose of 7.5 mg/kg
of body weight was administered to five healthy volunteers as a 5-min intravenous …

Antitumor 1-(X-aryl)-3, 3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity …

C Hansch, GJ Hatheway, FR Quinn… - Journal of Medicinal …, 1978 - ACS Publications
… They conclude that DTIC kills cells most effectively in the Gj and early S phase and that it is
only moderately lethal to cells in other phases of the cell cycle. This evidence in mammalian …

Centrally acting emetics. 10. Rigid dopamine congeners derived from octahydrobenzo [f] quinoline

JG Cannon, GJ Hatheway, JP Long… - Journal of Medicinal …, 1976 - ACS Publications
In a study of conformational requirements for certain dopaminergic agonist molecules, a
series of conformationally predictable dopamine congeners related to cis-and trons-…

Inhibition of the sympathetic nervous system by a series of heterocyclic congeners of dopamine.

…, JP Long, JG Cannon, GJ Hatheway - Journal of Pharmacology …, 1976 - ASPET
A series of heterocyclic congeners of dopamine (GJH-series) with different positions of
phenolic oxygens and with the possibility of cis and trans isomerism at the 4a-10b ring juncture …

Doxycycline-induced esophagitis

GJ Hatheway - Drug Intelligence & Clinical Pharmacy, 1982 - journals.sagepub.com
Hatheway, 1982 … HathewayHatheway

[BOOK][B] HETEROCYCLIC CONGENERS OF DOPAMINE.

GJ Hatheway - 1975 - search.proquest.com
… Gerard John Hatheway … Gerard John Hatheway … 9 GJ 9 ) 9 …

[CITATION][C] Problems with administration devices for commercially available nitroglycerin injection

LA Little, GJ Hatheway - American Journal of Hospital Pharmacy, 1982 - academic.oup.com
… Little and Hatheway conclude that "these products were released before completion of a …
promotional material, as do Little and Hatheway. Considerable research continues with ,Tridil to …

Correction to Metronidazole Structure

GJ Hatheway - Drug Intelligence & Clinical Pharmacy, 1982 - journals.sagepub.com
Hatheway, 1982 … Hatheway, Pharm.D., Ph.D.… Hatheway, Pharm.D., Ph.D. …