A model proposing that N-methyl-d-aspartate (NMDA) receptor and opioid receptor mechanisms
overlap and interact within the same dorsal horn nociceptive neurons makes several …

: Combined oral administration of morphine sulfate (MS) and the over-the-counter antitussive
drug and N-methyl-D-aspartate receptor antagonist dextromethorphan (DM) prevented the …

Dextromethorphan (DM), a structural analog of morphine and codeine, has been widely used
as a cough suppressant for more than 40 years. DM is not itself a potent analgesic, but it …

Indapamide is a new antihypertensive diuretic agent indicated for the treatment of hypertension
and edema. Indapamide shows an alteration in vascular reactivity to calcium and other …

The opioid agonist properties of (±)-methadone are ascribed almost entirely to the (−)-methadone
enantiomer. To extend our knowledge of the pharmacological actions of methadone at …

Celiprolol, a new beta-adrenoccptor antagonist, blocks serotonin-and methacholine-mediated
bronchoconstriction in animals (1, 2), even in the presence of propranolol (3). In two, …

and Conclusions Informed consent was obtained from over 350 patients scheduled for major
elective operations to accept either 5 or 10 mg morphine or 0.5 or 1.0 mg butorphanol (…

The effects of combined single oral treatments with non-steroidal anti-inflammatory drugs (NSAIDs)
and the non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist …

Either butorphanol tartrate (1, 2, or 4 mg) or pentazocine (30 or 60 mg) was given intramuscularly
(5 dose groups) to 262 patients, who were scheduled for major operations, if they had …

The acute and sub-acute toxicity of potassium niobate and niobium pentachloride has been
investigated. Single intravenous doses of 20 mg Nb/kg or less to rats, rabbits, and dogs were …