The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria
…, C Cepanec, D Pessayre, F Degoul - Pharmacogenetics …, 2003 - journals.lww.com
A genetic dimorphism encodes for either alanine (Ala) or valine (Val) in the mitochondrial
targeting sequence (MTS) of human manganese superoxide dismutase (MnSOD) and has …
targeting sequence (MTS) of human manganese superoxide dismutase (MnSOD) and has …
The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability
…, S Cazanave, D Pessayre, F Degoul - Pharmacogenetics …, 2005 - journals.lww.com
A genetic dimorphism incorporates either alanine (Ala) or valine (Val) in the mitochondrial
targeting sequence (MTS) of manganese superoxide dismutase (MnSOD). The Ala-MTS …
targeting sequence (MTS) of manganese superoxide dismutase (MnSOD). The Ala-MTS …
The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA
M Helm, H Brulé, F Degoul, C Cepanec… - Nucleic acids …, 1998 - academic.oup.com
Direct sequencing of human mitochondrial tRNA Lys shows the absence of editing and the
occurrence of six modified nucleotides (m 1 A9, m 2 G10, Ψ27, Ψ28 and hypermodified …
occurrence of six modified nucleotides (m 1 A9, m 2 G10, Ψ27, Ψ28 and hypermodified …
Annexin A1 localization and its relevance to cancer
…, B Bouchon, C Viallard, M D'Incan, F Degoul - Clinical …, 2016 - portlandpress.com
Annexin A1 (ANXA1) is a Ca 2+ -regulated phospholipid-binding protein involved in various
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …
A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency
E Boitier, F Degoul, I Desguerre, C Charpentier… - Journal of the …, 1998 - Elsevier
We report severe coenzyme Q 10 deficiency of muscle in a 4-year-old boy presenting with
progressive muscle weakness, seizures, cerebellar syndrome, and a raised cerebro–spinal …
progressive muscle weakness, seizures, cerebellar syndrome, and a raised cerebro–spinal …
Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease
F Degoul, A Sutton, A Mansouri, C Cepanec, D Valla… - Gastroenterology, 2001 - Elsevier
Background & Aims: For similar ethanol consumption, a some subjects only develop
macrovacuolar steatosis whereas others develop severe liver lesions. A genetic dimorphism …
macrovacuolar steatosis whereas others develop severe liver lesions. A genetic dimorphism …
Antibody pretargeting based on bioorthogonal click chemistry for cancer imaging and targeted radionuclide therapy
A Rondon, F Degoul - Bioconjugate Chemistry, 2019 - ACS Publications
Bioorthogonal click chemistry—employing antibody-conjugated trans-cyclooctenes (TCO)
and tetrazine (Tz)-based radioligands able to covalently bind in vivo—appeared recently as a …
and tetrazine (Tz)-based radioligands able to covalently bind in vivo—appeared recently as a …
Annexin A1 in primary tumors promotes melanoma dissemination
…, M Bonnet, M D'Incan, F Degoul - Clinical & experimental …, 2014 - Springer
Metastatic melanoma is one of the most aggressive forms of skin cancer and has a poor
prognosis. We have previously identified Annexin A1 (ANXA1) as a potential murine melanoma-…
prognosis. We have previously identified Annexin A1 (ANXA1) as a potential murine melanoma-…
[HTML][HTML] Radioimmunotherapy in oncology: overview of the last decade clinical trials
Simple Summary Monoclonal antibody-bearing radionuclides have been under clinical
investigation over the last two decades for their use in theranostic (diagnostic and therapeutic) …
investigation over the last two decades for their use in theranostic (diagnostic and therapeutic) …
[HTML][HTML] Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing
A Voissiere, E Jouberton, E Maubert, F Degoul… - PLoS …, 2017 - journals.plos.org
It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor,
is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the …
is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the …