User profiles for F. Pérez-Vizcaı́no
Prof. FRANCISCO PEREZ VIZCAINO (ORCID 0000-0001-6309-7418)School of Medicine. Universidad Complutense de Madrid. Spain Verified email at ucm.es Cited by 12592 |
Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries
F Pérez-Vizcaı́no, M Ibarra, AL Cogolludo… - … of Pharmacology and …, 2002 - ASPET
The flavonoid quercetin is metabolized into isorhamnetin, tamarixetin, and kaempferol, the
vascular effects of which are unknown. In the present study, the effects of quercetin and its …
vascular effects of which are unknown. In the present study, the effects of quercetin and its …
[PDF][PDF] Protección cardiovascular con flavonoides: enigma farmacocinético
J Duarte, F Pérez-Vizcaíno - Ars Pharmaceutica (Internet), 2015 - SciELO Espana
Objetivos. Los flavonoides ejercen efectos beneficiosos en la prevención de las
enfermedades cardiovasculares. En esta revisión trataremos de clarificar algunas preguntas …
enfermedades cardiovasculares. En esta revisión trataremos de clarificar algunas preguntas …
Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats
…, M Angeles Ocete, F Pérez‐Vizcaino… - British journal of …, 2001 - Wiley Online Library
The effects of an oral daily dose (10 mg kg −1 ) of the flavonoid quercetin for 5 weeks in
spontaneously hypertensive (SHR) and normotensive Wistar Kyoto rats (WKY) were analysed. …
spontaneously hypertensive (SHR) and normotensive Wistar Kyoto rats (WKY) were analysed. …
Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats
Results In SHR, quercetin reduced the increase in blood pressure and heart rate and
enhanced the endothelium-dependent aortic vasodilation induced by acetylcholine, but had no …
enhanced the endothelium-dependent aortic vasodilation induced by acetylcholine, but had no …
Vasodilator effects of quercetin in isolated rat vascular smooth muscle
The effects of quercetin were studied on contractile responses induced by noradrenaline,
high KCl, Ca 2+ and phorbol 12-myristate, 13-acetate in rat aortic strips and on spontaneous …
high KCl, Ca 2+ and phorbol 12-myristate, 13-acetate in rat aortic strips and on spontaneous …
Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt …
…, J Tamargo, F Vargas, F Pérez-Vizcaíno… - Free Radical Biology …, 2012 - Elsevier
Flavanol-rich diets have been reported to exert beneficial effects in preventing cardiovascular
diseases, such as hypertension. We studied the effects of chronic treatment with …
diseases, such as hypertension. We studied the effects of chronic treatment with …
SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging
…, Z Ungvary, F Pérez-Vizcaíno… - Biochemical …, 2013 - Elsevier
Vascular aging is characterized by up-regulation of NADPH oxidase, oxidative stress and
endothelial dysfunction. Previous studies demonstrate that the activity of the evolutionarily …
endothelial dysfunction. Previous studies demonstrate that the activity of the evolutionarily …
Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats
…, F Vargas, F Pérez-Vizcaíno… - Journal of …, 2002 - journals.lww.com
Objectives The present study analysed, for the first time, the effects of the flavonoid quercetin
in rats after chronic inhibition of nitric oxide (NO) synthesis with N ω-nitro-l-arginine methyl …
in rats after chronic inhibition of nitric oxide (NO) synthesis with N ω-nitro-l-arginine methyl …
Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC
Chronic administration of the most abundant dietary flavonoid quercetin exerts antihypertensive
effects and improves endothelial function. We have investigated the effects of quercetin …
effects and improves endothelial function. We have investigated the effects of quercetin …
Serotonin Inhibits Voltage-Gated K+ Currents in Pulmonary Artery Smooth Muscle Cells: Role of 5-HT2A Receptors, Caveolin-1, and KV1.5 Channel Internalization
…, L Cobeno, J Tamargo, F Perez-Vizcaino - Circulation …, 2006 - Am Heart Assoc
Multiple lines of evidence indicate that serotonin (5-hydroxytryptamine [5-HT]) and voltage-gated
K + (K V ) channels play a central role in the pathogenesis of pulmonary hypertension (…
K + (K V ) channels play a central role in the pathogenesis of pulmonary hypertension (…