A Water‐Soluble Cyclic Selenide with Enhanced Glutathione Peroxidase‐Like Catalytic Activities

F Kumakura, B Mishra, KI Priyadarsini, M Iwaoka - 2010 - Wiley Online Library
Antioxidative catalytic activities of trans‐3,4‐dihydroxyselenolane (DHS red ), a water‐soluble
cyclic selenide, were investigated in the reaction of hydrogen peroxide with three different …

Urinary incontinence in pregnant women and its relation with socio-demographic variables and quality of life

…, PF Cansi, RFDC Consentino, FY Kumakura… - Revista da Associação …, 2013 - Elsevier
Objective To investigate the occurrence of urinary incontinency (UI) in pregnant women and
its relationship with socio-demographic variables and quality of life. Methods A descriptive …

[PDF][PDF] Antioxidative glutathione peroxidase activity of selenoglutathione

S Yoshida, F Kumakura, I Komatsu, K Arai… - Angewandte …, 2011 - academia.edu
… When an insufficient amount of GSH is present in the solution, another cycle of processes
a, d, and e and a bypass process (f) would rescue the reaction. The bypass cycle should …

Effects of ring size and polar functional groups on the glutathione peroxidase-like antioxidant activity of water-soluble cyclic selenides

K Arai, F Kumakura, M Takahira… - The Journal of …, 2015 - ACS Publications
To elucidate the effects of ring structure and a substituent on the glutathione peroxidase- (GPx-)
like antioxidant activities of aliphatic selenides, series of water-soluble cyclic selenides …

Applications of water-soluble selenides and selenoxides to protein chemistry

M Iwaoka, F Kumakura - Phosphorus, Sulfur, and Silicon, 2008 - Taylor & Francis
Two water-soluble organic selenides, 3,3′-selenodipropanonic acid and 2-selenanecarboxylic
acid, were synthesized and reversibly converted to the corresponding selenoxides in …

One-electron redox processes in a cyclic selenide and a selenoxide: a pulse radiolysis study

BG Singh, E Thomas, F Kumakura… - The Journal of …, 2010 - ACS Publications
… Linear plot for the observed first order rate constant (k f ) for the formation of the transient at
480 nm on pulse radiolysis of N 2 saturated aqueous solution containing 0.5 M t-butyl alcohol …

Antinociceptive effects of AS1892802, a novel Rho kinase inhibitor, in rat models of inflammatory and noninflammatory arthritis

E Yoshimi, F Kumakura, C Hatori, E Hamachi… - … of Pharmacology and …, 2010 - ASPET
Rho kinase (ROCK) is involved in various physiological functions, including cell motility,
vasoconstriction, and neurite extension. Although a functional role of ROCK in nociception in the …

Alleviating effects of AS1892802, a Rho kinase inhibitor, on osteoarthritic disorders in rodents

…, E Yoshimi, C Hatori, F Kumakura… - Journal of …, 2011 - jstage.jst.go.jp
… HIG82 cells were cultured in Ham’s F-12 medium supplemented with 10% fetal calf serum
and then the medium was replaced with serum-free Ham’s F-12 medium containing 0.1% bo…

Role of substrate reactivity in the glutathione peroxidase (GPx) activity of selenocystine

BG Singh, PP Bag, F Kumakura… - Bulletin of the …, 2010 - academic.oup.com
Selenocystine (CysSeSeCys), a diselenide, exhibits glutathione peroxidase (GPx) activity,
where it catalyses the reduction of hydroperoxides using a thiol co-factor. To understand the …

Fatty Acid Conjugates of Water‐Soluble (±)‐trans‐Selenolane‐3,4‐diol: Effects of Alkyl Chain Length on the Antioxidant Capacity

…, M Noguchi, K Takahashi, F Kumakura… - …, 2015 - Wiley Online Library
Fatty acid monoesters of the title compound (DHS red ), of variable carbon chain length (propionate,
laurate, myristate, palmitate, and stearate), were synthesized, and their antioxidant …