Cyclodextrins are widely used excipients, composed of glucopyranose units with a cyclic
structure. One of their most important properties, is that their inner cavity is hydrophobic, while …

Biological barriers are the main defense systems of the homeostasis of the organism and
protected organs. The blood–brain barrier (BBB), formed by the endothelial cells of brain …

Several β-cyclodextrin (β-CD) derivatives have been synthesized recently to improve the
physicochemical properties and inclusion capacities of the parent molecule, however, there is …

Self-emulsifying drug delivery systems (SEDDS) are regarded as a potential implement for
oral delivery of water insoluble APIs to overcome their poor and irregular bioavailability. The …

The objective of this study was to examine the cellular effects of the members of two non-ionic
amphiphilic tenside groups and their mixtures on human Caco-2 cell monolayers as …

Since the discovery about 30 years ago (2-hydroxypropyl) beta-cyclodextrin, a highly soluble
derivative of beta-cyclodextrin, has become an approved excipient of drug formulations …

… (F) The ratio of the fluorescence intensity of the NF-kB immunostaining in cell nuclei and
cytosol was analyzed (n = 3 per genotype). (G) RT-qPCR measurements on the indicated …

Cyclodextrins are widely used excipients for increasing the bioavailability of poorly water-soluble
drugs. Their effect on drug absorption in the gastrointestinal tract is explained by their …

Cyclodextrins, even the 6-membered α-cyclodextrin, are approved in the various
pharmacopoeias as pharmaceutical excipients for solubilizing and stabilizing drugs as well as for …

Chrysin is a bioflavonoid that can be found in natural products such as honey and propolis,
and it possesses several biological effects such as antioxidant, anti-inflammatory, and anti-…