As part of an effort to examine gender-related differences in the abuse liability of morphine,
the present parametric study was undertaken to systematically establish whether there are …

Gender differences have been observed in a number of aspects of the pharmacology of opiates,
including their antinociceptive activity, discriminative stimulus properties, the generation …

The purpose of the present studies was to determine the role of either the organizational or
activational sex steroids in mediating the sex differences observed in morphine-induced …

… Moreover, we found that the ED … ED 50 values in the hot-plate test, groups of rats received
injections with four or five doses of morphine or alfentanil falling between the ED 10 and ED …

Two narcotic antagonists, naloxone and naltrexone, significantly elevated serum LH levels in
male rats within minutes after their sc injection. The peak increase in serum LH occurred 20 …

In earlier studies, it was shown that there were gender differences in several aspects of the
pharmacological profile of morphine, including its antinociceptive activity, discriminative …

The purpose of the present studies was to examine whether gender differences could be
observed in an important aspect of morphine's pharmacology: its reinforcing properties. Our …

Two sediment cores drawn from springs in the Cuatro Cienegas Basin, a small desert valley
in central Coahuila, yielded fossil pollen chronologies transgressing more than 30,000 …

The effects of opioids on testicular function were assessed in the rat through measurements
of serum testosterone levels, testicular interstitial fluid (TIF) formation and TIF testosterone …

The effects of nitric oxide (NO)-related agents on testicular function were examined in male
rats with measurements of serum luteinizing hormone, serum testosterone, testicular …