Interlaboratory assessment of the bovine corneal opacity and permeability (BCOP) assay
…, G Haynes, JA Vericat, R Pirovano, EG Tos… - Toxicology in vitro, 1994 - Elsevier
A multinational interlaboratory study to investigate the bovine corneal opacity and permeability
(BCOP) assay is presented. The aim of this work was to determine the capability and …
(BCOP) assay is presented. The aim of this work was to determine the capability and …
Bentamapimod (JNK inhibitor AS602801) induces regression of endometriotic lesions in animal models
SS Palmer, M Altan, D Denis, EG Tos… - Reproductive …, 2016 - Springer
Endometriosis is an estrogen (ER)-dependent gynecological disease caused by the growth
of endometrial tissue at extrauterine sites. Current endocrine therapies address the …
of endometrial tissue at extrauterine sites. Current endocrine therapies address the …
Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2α receptor (FP)
R Cirillo, EG Tos, P Page, M Missotten… - American journal of …, 2007 - Elsevier
OBJECTIVE: The purpose of this study was to assess the tocolytic effect of AS604872, an
orally active, potent, and selective prostanoid prostaglandin F2α receptor (FP) antagonist. …
orally active, potent, and selective prostanoid prostaglandin F2α receptor (FP) antagonist. …
Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists
…, A Nichols, R Cirillo, EG Tos… - Journal of medicinal …, 2005 - ACS Publications
We report a novel chemical class of potent oxytocin receptor antagonists showing a high
degree of selectivity against the closely related vasopressin receptors (V1a, V1b, V2). An initial …
degree of selectivity against the closely related vasopressin receptors (V1a, V1b, V2). An initial …
Pharmacological inhibition of phosphodiesterase 4 triggers ovulation in follicle-stimulating hormone-primed rats
SD McKenna, M Pietropaolo, EG Tos, A Clark… - …, 2005 - academic.oup.com
… Enrico Gillio Tos , Enrico Gillio Tos … McKenna, Michael Pietropaolo, Enrico Gillio Tos,
Ann Clark, David Fischer, David Kagan, Bagna Bao, P. Jorge Chedrese, Stephen Palmer, …
Ann Clark, David Fischer, David Kagan, Bagna Bao, P. Jorge Chedrese, Stephen Palmer, …
Pharmacology of (2S, 4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2′-methyl [1, 1′-biphenyl]-4-yl) carbonyl]-2-pyrrolidinecarboxamide, a new potent …
R Cirillo, EG Tos, MK Schwarz, A Quattropani… - … of Pharmacology and …, 2003 - ASPET
… nonpregnant rats, single administration of compound 1 by iv or oral routes causes dose-dependent
inhibition of contractions elicited by repeated injections of oxytocin with ED 50 = 3.5 …
inhibition of contractions elicited by repeated injections of oxytocin with ED 50 = 3.5 …
[HTML][HTML] Tocolytic effect of a selective FP receptor antagonist in rodent models reveals an innovative approach to the treatment of preterm labor
A Chollet, EG Tos, R Cirillo - BMC Pregnancy and Childbirth, 2007 - Springer
Background Management of preterm labor by tocolysis remains an unmet medical need.
Prostaglandins play a major role in regulation of uterine activity and in molecular mechanisms …
Prostaglandins play a major role in regulation of uterine activity and in molecular mechanisms …
Risk of high-grade cervical intraepithelial neoplasia during follow-up in HPV-positive women according to baseline p16-INK4A results: a prospective analysis of a …
F Carozzi, A Gillio-Tos, M Confortini… - The lancet …, 2013 - thelancet.com
Background Immunostaining for p16-INK4A (henceforth p16) is a sensitive and specific
method for detection of high-grade cervical intraepithelial neoplasia (CIN) in women infected …
method for detection of high-grade cervical intraepithelial neoplasia (CIN) in women infected …
Hypermethylation, risk factors, clinical characteristics, and survival in 235 patients with laryngeal and hypopharyngeal cancers
RP Dikshit, A Gillio‐Tos, P Brennan, L De Marco… - Cancer, 2007 - Wiley Online Library
… Hypermethylation was present in 44% of samples for p16, in 27% of samples for MGMT, in
42% of samples for DAP‐K, and in 43% of samples for E‐cadherin. Hypermethylation of either …
42% of samples for DAP‐K, and in 43% of samples for E‐cadherin. Hypermethylation of either …
Lymphokine-activated killer (LAK) cell activity in B and T chronic lymphoid leukemia: defective LAK generation and reduced susceptibility of the leukemic cells to …
…, M Bonferroni, S Cardona, A Guarini, AG Tos… - 1990 - ashpublications.org
… cells and various numbers of effector cells at final effector/target (E/T) ratios of 50:1,25:1, 12:1…
according to the following formula: (E - S)/(M - S) x 100 (where E = mean cpm release in the …
according to the following formula: (E - S)/(M - S) x 100 (where E = mean cpm release in the …