Family of BODIPY photocages cleaved by single photons of visible/near-infrared light

JA Peterson, C Wijesooriya, EJ Gehrmann… - Journal of the …, 2018 - ACS Publications
Photocages are light-sensitive chemical protecting groups that provide external control over
when, where, and how much of a biological substrate is activated in cells using targeted …

Efficient far-red/near-IR absorbing BODIPY photocages by blocking unproductive conical intersections

…, KC Dissanayake, EJ Gehrmann… - Journal of the …, 2020 - ACS Publications
Photocages are light-sensitive chemical protecting groups that give investigators control over
activation of biomolecules using targeted light irradiation. A compelling application of far-…

A Photoactivatable BODIPY Probe for Localization‐Based Super‐Resolution Cellular Imaging

…, JA Peterson, P Shrestha, EJ Gehrmann… - Angewandte …, 2018 - Wiley Online Library
The synthesis and application of a photoactivatable boron‐alkylated BODIPY probe for
localization‐based super‐resolution microscopy is reported. Photoactivation and excitation of the …

Prolonged immunomodulation in inflammatory arthritis using the selective Kv1. 3 channel blocker HsTX1 [R14A] and its PEGylated analog

MR Tanner, RB Tajhya, R Huq, EJ Gehrmann… - Clinical …, 2017 - Elsevier
Effector memory T lymphocytes (T EM cells) that lack expression of CCR7 are major drivers
of inflammation in a number of autoimmune diseases, including multiple sclerosis and …

Direct photorelease of alcohols from boron-alkylated BODIPY photocages

JA Peterson, LJ Fischer, EJ Gehrmann… - The Journal of …, 2020 - ACS Publications
BODIPY photocages allow the release of substrates using visible light irradiation. They have
the drawback of requiring reasonably good leaving groups for photorelease. Photorelease …

Photocaged DNA-Binding Photosensitizer Enables Photocontrol of Nuclear Entry for Dual-Targeted Photodynamic Therapy

…, S Ayan, P Shrestha, EJ Gehrmann… - Journal of Medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a clinically approved cancer treatment that requires a
photosensitizer (PS), light, and molecular oxygen─a combination which produces reactive oxygen …

Targeting KCa1. 1 channels with a scorpion venom peptide for the therapy of rat models of rheumatoid arthritis

…, BH Chamberlain, R Huq, EJ Gehrmann… - … of Pharmacology and …, 2018 - ASPET
Fibroblast-like synoviocytes (FLSs) are a key cell type involved in rheumatoid arthritis (RA)
progression. We previously identified the KCa1.1 potassium channel (Maxi-K, BK, Slo 1, …

Use of DNA end joining activity of a Xenopus laevis egg extract for construction of deletions and expression vectors for HIV-1 Tat and Rev proteins

H Schaal, P Pfeiffer, M Klein, P Gehrmann, A Scheid - Gene, 1993 - Elsevier
… joining (EJ) activity of an extract from Xenopus laevis eggs. The nonhomologous EJ activity
… laevis egg extracts for intramolecular nonhomologous EJ proved to be a powerful tool, as …

Winters are changing: snow effects on Arctic and alpine tundra ecosystems

…, TGW Forte, ER Frei, SR Geange, F Gehrmann… - Arctic …, 2022 - cdnsciencepub.com
Snow is an important driver of ecosystem processes in cold biomes. Snow accumulation
determines ground temperature, light conditions, and moisture availability during winter. It also …

The two-loop helicity amplitudes for leptons

T Gehrmann, A von Manteuffel, L Tancredi - Journal of High Energy …, 2015 - Springer
… expansion of the form factors Ej defined in a completely … in [32], such that our form factors
Ej can be mapped one to one to the Fj … arrangements C contributing to the functions Aj and Ej, …