Amiloride and its analogs as tools in the study of ion transport.
TR Kleyman, EJ Cragoe Jr - The Journal of membrane biology, 1988 - europepmc.org
Amiloride inhibits most plasma membrane Na+ transport systems. We have reviewed the
pharmacology of inhibition of these transporters by amiloride and its analogs. Thorough studies …
pharmacology of inhibition of these transporters by amiloride and its analogs. Thorough studies …
Participation of a K+ channel modulated directly by cGMP in the speract-induced signaling cascade of Strongylocentrotus purpuratus sea urchin sperm
BE Galindo, C Beltrán, EJ Cragoe Jr, A Darszon - Developmental biology, 2000 - Elsevier
Speract, a decapeptide from Strongylocentrotus purpuratus sea urchin eggs, transiently
stimulates a membrane guanylyl cyclase and activates a K + -selective channel that …
stimulates a membrane guanylyl cyclase and activates a K + -selective channel that …
Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger
…, P Barbry, P Vigne, O Chassande, EJ Cragoe Jr… - Biochimie, 1988 - Elsevier
Amiloride analogs inhibit a number of transmembrane Na + transport systems: 1) the
epithelium Na + channel, 2) the Na + /H + exchange system and 3) the Na + /Ca 2+ exchange …
epithelium Na + channel, 2) the Na + /H + exchange system and 3) the Na + /Ca 2+ exchange …
NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na (+)-H+ exchange
…, MC Madden, EJ Cragoe Jr… - American Journal …, 1993 - journals.physiology.org
… Cala, PM, SE Anderson, and EJ Cragoe. Na/H exchange-dependent cell volume and pH …
Kleyman, TR, and EJ Cragoe. Amiloride and its analogs as tools in the study of ion transport…
Kleyman, TR, and EJ Cragoe. Amiloride and its analogs as tools in the study of ion transport…
[HTML][HTML] An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.
…, S Brandon, AL Wilson, CA Guyer, EJ Cragoe Jr… - Journal of Biological …, 1990 - Elsevier
The residue involved in sodium regulation of G-protein-coupled receptors has been identified
by site-directed mutagenesis of the alpha 2-adrenergic receptor gene. Mutation of Asp-79 …
by site-directed mutagenesis of the alpha 2-adrenergic receptor gene. Mutation of Asp-79 …
Pyrazine diuretics. II. N-amidino-3-amino-5-substituted 6-halopyrazinecarboxamides
EJ Cragoe, OW Woltersdorf, JB Bicking… - Journal of medicinal …, 1967 - ACS Publications
The synthesis of a series of N-umidino-3-amino-5-substituted O-halopyrazinecarboxamides
is described. In rats and dogs, these compounds cause diuresis and saluresis while …
is described. In rats and dogs, these compounds cause diuresis and saluresis while …
Purification and reconstitution of chloride channels from kidney and trachea
Chloride channels mediate absorption and secretion of fluid in epithelia, and the regulation
of these channels is now known to be defective in cystic fibrosis. Indanyl-oxyacetic acid 94 (…
of these channels is now known to be defective in cystic fibrosis. Indanyl-oxyacetic acid 94 (…
The mechanism of action of amiloride.
TR Kleyman, EJ Cragoe Jr - Seminars in nephrology, 1988 - europepmc.org
Amiloride induces a mild natriuresis as well as antikaliuresis. These changes in salt excretion
are due to direct inhibition of the sodium channel in the apical plasma membrane of the …
are due to direct inhibition of the sodium channel in the apical plasma membrane of the …
Regulation of human neutrophil chemotaxis by intracellular pH.
L Simchowitz, EJ Cragoe Jr - Journal of Biological Chemistry, 1986 - Elsevier
The relationship of N-formyl-methionyl-leucyl-phenylalanine-stimulated Na+/H+ exchange
to the chemotactic responsiveness of human neutrophils was investigated. The pHi changes, …
to the chemotactic responsiveness of human neutrophils was investigated. The pHi changes, …
[HTML][HTML] Regulation of intracellular pH in cultured hippocampal neurons by an amiloride-insensitive Na+/H+ exchanger.
KM Raley-Susman, EJ Cragoe Jr, RM Sapolsky… - Journal of Biological …, 1991 - Elsevier
Regulation of intracellular pH (pHi) in single cultured rat hippocampal neurons was investigated
using the fluorescent pHi indicator dye bis-carboxyethylcarboxyfluorescein. Resting pHi …
using the fluorescent pHi indicator dye bis-carboxyethylcarboxyfluorescein. Resting pHi …