D1 receptors in prefrontal cells and circuits

PS Goldman-Rakic, EC Muly III, GV Williams - Brain Research Reviews, 2000 - Elsevier
A worthy goal of systems neuroscience is to dissect the cellular and circuit basis of behavior
in order to extend the insights gained from the study of normal brain organization in animal …

Dopaminergic regulation of cerebral cortical microcirculation

LS Krimer, EC Muly, GV Williams… - Nature …, 1998 - nature.com
Functional variations in cerebral cortical activity are accompanied by local changes in blood
flow, but the mechanisms underlying this physiological coupling are not well understood. …

Molecular mechanisms of working memory

ZU Khan, EC Muly - Behavioural brain research, 2011 - Elsevier
Working memory is a process for temporary active maintenance of information and the role
of prefrontal cortex in this memory has been known since the pioneering experiments of …

D1 receptor in interneurons of macaque prefrontal cortex: distribution and subcellular localization

EC Muly, K Szigeti… - Journal of Neuroscience, 1998 - Soc Neuroscience
Working memory performance is influenced by dopamine activation of D1 family dopamine
receptors in the prefrontal cortex; working memory performance is maximal at moderate …

Memory deficits in aging and neurological diseases

…, E Martín-Montañez, I Navarro-Lobato, EC Muly - Progress in molecular …, 2014 - Elsevier
Memory is central to our ability to perform daily life activities and correctly function in society.
Improvements in public health and medical treatment for a variety of diseases have resulted …

Penetrance and pleiotropy of polygenic risk scores for schizophrenia, bipolar disorder, and depression among adults in the US veterans affairs health care system

…, A Mank, N Mahdavi, G Villarreal, EC Muly… - JAMA …, 2022 - jamanetwork.com
Importance Serious mental illnesses, including schizophrenia, bipolar disorder, and depression,
are heritable, highly multifactorial disorders and major causes of disability worldwide. …

Distribution of mGluR1α and mGluR5 immunolabeling in primate prefrontal cortex

EC Muly, M Maddox, Y Smith - Journal of Comparative …, 2003 - Wiley Online Library
… Results of this study have previously been reported in abstract form (Muly et al., 2002). … this
study as well as of other proteins in previous studies (Muly et al., 1998, 2001; Alagarsamy et al…

The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated …

…, MAG Marker, CJ Loweth, EC Muly… - Journal of …, 2013 - Soc Neuroscience
Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) is a
significant source of disability in the HIV-infected population. Even with stringent adherence to …

Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: localization to and within dendritic spines

EC Muly, Y Smith, P Allen… - Journal of Comparative …, 2004 - Wiley Online Library
… localized in the group of spines that contains both isoforms (Muly et al., 2001a). Thus, the …
Preliminary results of this study have been reported previously in abstract form (Muly et al., …

Immunohistochemical characterization of parvalbumin-containing interneurons in the monkey basolateral amygdala

F Mascagni, EC Muly, DG Rainnie, AJ McDonald - Neuroscience, 2009 - Elsevier
Interneurons expressing the calcium-binding protein parvalbumin (PV) are a critical component
of the inhibitory circuitry of the basolateral nuclear complex (BLC) of the mammalian …