Mast cells are well known for their involvement in allergic and anaphylactic reactions, during
which immunoglobulin E (IgE) receptor (FcɛRI) aggregation leads to exocytosis of the …

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China. …

1 Mast cells participate in allergies, and also in immunity and inflammation by secreting
proinflammatory cytokines. 2 Flavonoids are naturally occurring polyphenolic plant compounds, …

Mast cells are critical for allergic reactions, but also for innate or acquired immunity and
inflammatory conditions that worsen by stress. Corticotropin-releasing hormone (CRH), which …

The peptide substance P (SP) has been implicated in inflammatory conditions, such as
psoriasis, where mast cells and VEGF are increased. A relationship between SP and VEGF has …

Interstitial cystitis (IC) is a heterogeneous syndrome of unknown etiology. Altered bladder
glycosaminoglycans lining and bladder mastocytosis have been documented in IC. The …

Current evidence from clinical and laboratory studies confirms that mast cells play a central
role in the pathogenesis and pathophysiology of interstitial cystitis (IC). In this article, we …

Several inflammatory skin conditions, including atopic dermatitis (AD) and psoriasis, are
exacerbated by stress. Recent evidence suggests that crosstalk between mast cells, neurons …

Neuroinflammatory response is primarily a protective mechanism in the brain. However,
excessive and chronic inflammatory responses can lead to deleterious effects involving immune …

IL-10 has been previously called cytokine synthesis inhibiting factor, produced mostly by
Th2 cells, macrophages and CD8+ cell clones. IL-10 is capable of inhibiting the synthesis of …