[HTML][HTML] Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
…, M Trejo, D Masliah, A Adame, E Masliah… - Acta neuropathologica …, 2017 - Springer
Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and
Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in …
Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in …
[HTML][HTML] Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and …
…, M Mante, A Adame, JA Fields, D Masliah… - Molecular …, 2018 - Springer
Background Synucleinopathies of the aging population are an heterogeneous group of
neurological disorders that includes Parkinson’s disease (PD) and dementia with Lewy bodies (…
neurological disorders that includes Parkinson’s disease (PD) and dementia with Lewy bodies (…
[PDF][PDF] Integrating gene and protein expression reveals perturbed functional networks in Alzheimer's disease
Asymptomatic and symptomatic Alzheimer's disease (AD) subjects may present with equivalent
neuropathological burdens but have significantly different antemortem cognitive decline …
neuropathological burdens but have significantly different antemortem cognitive decline …
Pharmacological and toxicological properties of the potent oral γ-secretase modulator BPN-15606
…, PD Nguyen, A Becker, U Vo, D Masliah… - Journal of pharmacology …, 2017 - ASPET
Alzheimer’s disease (AD) is characterized neuropathologically by an abundance of 1) neuritic
plaques, which are primarily composed of a fibrillar 42-amino-acid amyloid-β peptide (Aβ), …
plaques, which are primarily composed of a fibrillar 42-amino-acid amyloid-β peptide (Aβ), …
Increased vulnerability of the hippocampus in transgenic mice overexpressing APP and triple repeat tau
…, M Mante, J Florio, D Masliah… - Journal of …, 2018 - content.iospress.com
Alzheimer’s disease (AD) is the most common tauopathy, characterized by progressive
accumulation of amyloid-β (Aβ) and hyperphosphorylated tau. While pathology associated with …
accumulation of amyloid-β (Aβ) and hyperphosphorylated tau. While pathology associated with …
Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
…, J Florio, M Trejo, D Masliah… - Acta …, 2020 - actaneurocomms.biomedcentral …
… Jennifer Ngolab1, Ivy Trinh1, Edward Rockenstein1, Michael Mante1, Jazmin Florio1,
Margarita Trejo1, Deborah Masliah1, Anthony Adame1, Eliezer Masliah1,2 and Robert A …
Margarita Trejo1, Deborah Masliah1, Anthony Adame1, Eliezer Masliah1,2 and Robert A …
Perturbed functional networks in Alzheimer's Disease reveal opposing roles for TGIF and EGR3
While Alzheimer’s disease (AD) is the most prevalent cause of dementia, complex
combinations of the underlying pathologies have led to evolved concepts in clinical and …
combinations of the underlying pathologies have led to evolved concepts in clinical and …
Reversible ischemia increases levels of Alzheimer amyloid protein precursor without increasing levels of mRNA in the rabbit spinal cord
…, A Kittel, D Kang, D Shackelford, E Masliah… - Molecular brain …, 1997 - Elsevier
In a rabbit spinal cord ischemia model (RSCIM), the time courses of neuropathological damage
of the spinal cord and neurological impairment of the motor functions are well established…
of the spinal cord and neurological impairment of the motor functions are well established…
Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension
…, JM Roch, D Schubert, E Masliah… - Journal of …, 1994 - Soc Neuroscience
Amyloid beta/A4 protein precursor (APP) is secreted into medium by most cultured cells and
can function as an autocrine factor. To study the biological function of secreted forms of APP …
can function as an autocrine factor. To study the biological function of secreted forms of APP …
The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
A Iwai, E Masliah, M Yoshimoto, N Ge, L Flanagan… - Neuron, 1995 - cell.com
Non-Ap component of Alzheimefs disease amyloid (NAC) is the second component in the
amyloid from brain tissue of patients affected with Alzheimer's disease. Its precursor protein (…
amyloid from brain tissue of patients affected with Alzheimer's disease. Its precursor protein (…