Chemerin: a comprehensive review elucidating the need for cardiovascular research

DJ Ferland, SW Watts - Pharmacological research, 2015 - Elsevier
When chemerin was discovered in 1997, it was relegated to being a protein associated with
the normal skin function contrasting the setting of psoriasis. However, with the discovery of …

Chemerin as a driver of hypertension: a consideration

DJ Ferland, AE Mullick, SW Watts - American journal of …, 2020 - academic.oup.com
The protein chemerin (tazarotene-induced gene, TIG2; RARRES2) is a relatively new adipokine.
Many studies support that circulating chemerin levels associate strongly and positively …

Chemerin-induced arterial contraction is Gi-and calcium-dependent

DJ Ferland, ES Darios, RR Neubig, B Sjögren… - Vascular …, 2017 - Elsevier
Chemerin is an adipokine associated with increased blood pressure, and may link obesity
with hypertension. We tested the hypothesis that chemerin-induced contraction of the …

[HTML][HTML] Chemerin contributes to in vivo adipogenesis in a location-specific manner

DJ Ferland, H Garver, GA Contreras, GD Fink… - PLoS …, 2020 - journals.plos.org
Since chemerin’s identification as an adipokine, it has been associated with a number of
human diseases including diabetes and obesity. However, the basic scientific foundation for …

Different blood pressure responses in hypertensive rats following chemerin mRNA inhibition in dietary high fat compared to dietary high-salt conditions

DJ Ferland, ED Flood, H Garver, ST Yeh… - Physiological …, 2019 - journals.physiology.org
Chemerin is a contractile adipokine, produced in liver and fat, and removal of the protein by
antisense oligonucleotides (ASO) lowers blood pressure in the normal Sprague Dawley rat. …

[HTML][HTML] The chemerin knockout rat reveals chemerin dependence in female, but not male, experimental hypertension

…, N McMullen, CJ Sinal, RK Kumar, DJ Ferland… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Measures of the adipokine chemerin are elevated in multiple cardiovascular diseases, including
hypertension, but little mechanistic work has been done to implicate chemerin as being …

Whole-body but not hepatic knockdown of chemerin by antisense oligonucleotide decreases blood pressure in rats

DJ Ferland, B Seitz, ES Darios, JM Thompson… - … of Pharmacology and …, 2018 - ASPET
Chemerin is an inflammatory adipokine positively associated with hypertension and obesity.
The majority of chemerin derives from the liver and adipose tissue, however, their individual …

The persistence of active smooth muscle in the female rat cervix through pregnancy

DJ Ferland, ES Darios, SW Watts - American Journal of Obstetrics and …, 2015 - Elsevier
Objective A controversy exists as to whether functional smooth muscle exists in the cervix
before and during pregnancy, potentially continuous with the uterus. We hypothesized that …

Quantitative spectroscopy of photoionized clouds

GJ Ferland - Annual Review of Astronomy and Astrophysics, 2003 - annualreviews.org
… Reliability in the face of complexity is a central tension in all simulation physics (Ferland &
Savin 2001)—we need to get the right answer because we want to compare predictions with …

Chemerin as a Link between Hypertension and Obesity

DJ Ferland - 2020 - search.proquest.com
David J. Ferland Chemerin is a novel protein with growing recognition in the clinical
sphere ;ut limited ;asic science advancements. Hypertension and o;esity have strong positive …