The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system

DT Monaghan, RJ Bridges… - Annual review of …, 1989 - annualreviews.org
MONAGHAN, BRIDGES & COTMAN … T. Specific binding of 3H-kainic acid to reн ceptor
sites in rat brain. Mol. … Takemoto, T. 1978. Isolation and structural identification of …

Distribution of N-methyl-D-aspartate-sensitive L-[3H] glutamate-binding sites in rat brain

DT Monaghan, CW Cotman - Journal of Neuroscience, 1985 - Soc Neuroscience
N-methyl-D-aspartate (NMDA) is an acidic amino acid which depolarizes neurons by selectively
interacting with a distinct class of excitatory amino acid receptor. Recent evidence has …

Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity.

CW Cotman, DT Monaghan… - Annual review of …, 1988 - psycnet.apa.org
Describes the properties of the excitatory amino acid receptor classes, particularly those of
the N-methyl-{d}-aspartate (NMDA) class, and indicates how properties of this receptor permit …

The distribution of [3H] kainic acid binding sites in rat CNS as determined by autoradiography

DT Monaghan, CW Cotman - Brain research, 1982 - Elsevier
The distribution of [ 3 H]kainic acid (KA) binding sites in the rat CNS was determined by in
vitro autoradiography. KA sites are distributed throughout the CNS gray matter in an …

Anatomical organization of excitatory amino acid receptors and their pathways

CW Cotman, DT Monaghan, OP Ottersen… - Trends in …, 1987 - Elsevier
Synapses that employ excitatory amino acids (EAA) as their neurotransmitter use multiple
combinations of receptors, apparently yielding different functional properties. The most well-…

The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition

…, JA Beaton, RA Morrisett, DT Monaghan - Journal of …, 1994 - Soc Neuroscience
The relationship between four pharmacologically distinct NMDA receptor subtypes, identified
in radioligand binding studies, and the recently identified NMDA receptor subunits (NR1a-g…

Plasticity of hippocampal circuitry in Alzheimer's disease

JW Geddes, DT Monaghan, CW Cotman, IT Lott… - Science, 1985 - science.org
Two markers of neuronal plasticity were used to compare the response of the human central
nervous system to neuronal loss resulting from Alzheimer's disease with the response of …

The NMDA receptor as a target for cognitive enhancement

…, G Fang, MW Irvine, BM Costa, DT Monaghan… - …, 2013 - Elsevier
NMDA receptors (NMDARs) play an important role in neural plasticity including long-term
potentiation and long-term depression, which are likely to explain their importance for learning …

Anatomical distributions of four pharmacologically distinct 3HL-glutamate binding sites

DT Monaghan, VR Holets, DW Toy, CW Cotman - Nature, 1983 - nature.com
Glutamate is thought to serve as a major excitatory neurotrans-mitter throughout the central
nervous system (CNS) 1,2 ; electrophysiological studies indicate that its action is mediated …

Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape 'superslow'afterburst EPSC in rat hippocampus

…, TS Tsintsadze, B Feng, DT Monaghan… - The Journal of …, 2004 - Wiley Online Library
In conditions of facilitated synaptic release, CA3/CA1 synapses generate anomalously slow
NMDA receptor‐mediated EPSCs (EPSC NMDA ). Such a time course has been attributed to …