… (C and D) Glucagon (C) and insulin (D) secretion in the presence or absence of adomeglivant
(Ado; 1 μM), a selective glucagon receptor antagonist. (E and F) Glucagon (E) and insulin (…

… D, E and F shows the quantitative analysis of fluorescence intensities in the region of
interest (ROI) in frontal cortex (D), Olfactory Bulb (E) and small intestine (F). *(p<0.05). …

… 1, C and D). Human NASH samples showed a significant increase in the p47phox/… 4, B and
D). This is not surprising because these mice did not have oxidative stress and there was no …

… D. Western blot analysis of HMGB1 protein levels in the serum. Lanes 1–3 represent LC, …
4C and D). Cell treated with peroxynitrite scavenger FBA or AKT inhibitor had significantly …

Objectives: The aim of this prospective phase II, randomized, investigator-blinded study (NCT00690378)
was to compare the efficacy and safety of ceftazidime–avibactam and imipenem…

NAFLD is a clinically progressive disease with steatosis, inflammation, endothelial dysfunction
and fibrosis being the stages where clinical intervention becomes necessary. Lack of …

High circulatory insulin and leptin followed by underlying inflammation are often ascribed to
the ectopic manifestations in non-alcoholic fatty liver disease (NAFLD) but the exact …

The molecular events that link NADPH oxidase activation and the induction of Toll-like
receptor (TLR)-4 recruitment into hepatic lipid rafts in nonalcoholic steatohepatitis (NASH) are …

Although significant research data exist on the pathophysiology of nonalcoholic steatohepatitis
(NASH), finding an efficient treatment regimen for it remains elusive. The present study …

Background and Purpose: It is still a matter of debate whether delayed primary closure (DPC)
of dirty abdominal incisions reduces surgical site infections (SSIs) compared with primary …