Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

JRP Geiger, T Melcher, DS Koh, B Sakmann… - Neuron, 1995 - cell.com
Recording of glutamate-activated currents in membrane patches was combined with RT-PCR-mediated
AMPA receptor (AMPAR) subunit mRNA analysis in single identified cells of rat …

Early-Onset Epilepsy and Postnatal Lethality Associated with an Editing-Deficient GluR-B Allele in Mice

R Brusa, F Zimmermann, DS Koh, D Feldmeyer… - Science, 1995 - science.org
The arginine residue at position 586 of the GluR-B subunit renders heteromeric α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate
(AMPA)-sensitive glutamate receptor channels …

Paracrine interactions within islets of Langerhans

DS Koh, JH Cho, L Chen - Journal of molecular neuroscience, 2012 - Springer
Glucose supply fluctuates between meal and fasting periods and its consumption by the body
varies greatly depending on bodily metabolism. Pancreatic islets of Langerhans secrete …

Block of native Ca (2+)‐permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification.

DS Koh, N Burnashev, P Jonas - The Journal of physiology, 1995 - Wiley Online Library
1. The influence of intracellular factors on current rectification of different subtypes of native
alpha‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazoleproprionate receptors (AMPARs) was studied …

Artificial Ion Channel Formed by Cucurbit[n]uril Derivatives with a Carbonyl Group Fringed Portal Reminiscent of the Selectivity Filter of K+ Channels

…, DH Oh, I Seo, CS Park, SR Jung, DS Koh… - Journal of the …, 2004 - ACS Publications
Novel artificial ion channels (1 and 2) based on CB[n] (n = 6 and 5, respectively) synthetic
receptors with carbonyl-fringed portals (diameter 3.9 and 2.4 Å, respectively) can transport …

Bradykinin inhibits M current via phospholipase C and Ca2+ release from IP3-sensitive Ca2+ stores in rat sympathetic neurons

H Cruzblanca, DS Koh, B Hille - Proceedings of the …, 1998 - National Acad Sciences
A variety of intracellular signaling pathways can modulate the properties of voltage-gated ion
channels. Some of them are well characterized. However, the diffusible second messenger …

Ca (2+)‐permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus.

DS Koh, JR Geiger, P Jonas… - The Journal of …, 1995 - Wiley Online Library
… to 7-3 with KOH. The pipette solution for the perforated vesicles contained (mM): 120 KCl,
20 K2S04, 10 EGTA, 2 MgCl2, 2 Na2ATP, 10 Hepes; pH adjusted to 7-3 with KOH. Dual…

Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength

…, PJ Walla, MY Choi, DS Cafiso, DS Koh… - Nature structural & …, 2015 - nature.com
… All pipette solutions were adjusted to pH 7.2 with KOH and calibrated for free Ca 2+ with
a calcium ion–selective electrode (Thermo Electron Corporation). A patch pipette was …

[HTML][HTML] Size distribution of mouse Langerhans islets

J Jo, MY Choi, DS Koh - Biophysical journal, 2007 - cell.com
Pancreatic β-cells are clustered in islets of Langerhans, which are typically a few hundred
micrometers in a variety of mammals. In this study, we propose a theoretical model for the …

Stimulation of exocytosis without a calcium signal

…, DF Babcock, T Nguyen, DS Koh - The Journal of …, 1999 - Wiley Online Library
More than 30 years ago, Douglas ( Douglas & Rubin, 1961 ; Douglas, 1968 ) proposed that
intracellular Ca 2+ controls stimulus‐secretion coupling in endocrine cells, and Katz & Miledi …