Pharmacological potency of the order exhibited by ryanodine is usually associated with a
highly specific mechanism of action. The great variety of effects observed and the differences …

… parallels the regional .distribution of ACh, (Table n, Finally,' the postmortem rise In Ch levels
in the hlppocampus ie not slgnifioaatly changed by septal lesions (Freeman and Jenden, u~…

We correlated the in vivo 1 H Magnetic Resonance Spectroscopy (MRS) concentration of the
choline peak (CHO) with in vitrochemical measures of choline-containing compounds and …

… Freeman JJ, Choi RL, Jenden DJ. Plasma choline: its turnover and exchange with brain
choline. J … Jope RS, Jenden DJ. Choline and phospholipid metabolism and the synthesis of …

Microinjection of oxotremorine (a muscarinic agent) or carbachol into the pontomesencephalic
reticular formation in conscious cats causes atonia, cortical desynchronization and …

Background: Previous studies have shown that plasma free choline concentrations are
significantly decreased in many long‐term home total parenteral nutrition (TPN) patients. …

The effect of age on brain metabolite concentrations was evaluated using localized proton
magnetic resonance spectroscopy. This technique allows in vivo measurements of N-acetyl …

The synthesis of whole brain acetylcholine is reduced in two strains (C57BL and BALB/c) of
senescent mice. The incorporation of [U- 14 C]glucose into acetylcholine decreased in both …

Presynaptic calcium channels are key regulators of neurotransmitter release. Oocyte
expression studies suggest that cysteine string proteins are essential subunits or modulators of …

Choline and folate share methylation pathways and, in studies of rats, were shown to be
metabolically inter-related. To determine whether choline status is related to folate intake in …