User profiles for D. J. Duncker

Dirk-Jan Duncker

Hoogleraar Experimentele Cardiologie, Erasmus MC, Universitair Medisch Centrum …
Verified email at erasmusmc.nl
Cited by 24907

Regulation of coronary blood flow during exercise

DJ Duncker, RJ Bache - Physiological reviews, 2008 - journals.physiology.org
Exercise is the most important physiological stimulus for increased myocardial oxygen demand.
The requirement of exercising muscle for increased blood flow necessitates an increase …

Cardiovascular disease and COVID-19: a consensus paper from the ESC working group on coronary pathophysiology & microcirculation, ESC working group on …

…, G Derumeaux, M Dorobantu, DJ Duncker… - Cardiovascular …, 2021 - academic.oup.com
The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19).
Microvascular injury, endothelial dysfunction, and thrombosis resulting from viral infection or …

Connecting heart failure with preserved ejection fraction and renal dysfunction: the role of endothelial dysfunction and inflammation

…, MC Verhaar, WJ Paulus, DJ Duncker… - European journal of …, 2016 - Wiley Online Library
Renal dysfunction in heart failure with preserved ejection fraction ( HFpEF ) is common and
is associated with increased mortality. Impaired renal function is also a risk factor for …

Myocardial protection by brief ischemia in noncardiac tissue

…, RG Schoemaker, MA van den Doel, DJ Duncker… - Circulation, 1996 - Am Heart Assoc
… Whereas Duncker et al 8 observed that a decrease in body temperature from 39C to 35C …
Duncker was made possible by a fellowship of the Royal Netherlands Academy of Arts and …

An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with European Society of Cardiology Working Group on …

…, JD Abbott, L Badimon, DJ Duncker… - European heart …, 2020 - academic.oup.com
This consensus document, a summary of the views of an expert panel organized by the
European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the …

Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice

…, DJ Duncker, R de Crom, DJ Lefer - Proceedings of the …, 2003 - National Acad Sciences
Congestive heart failure results in cardiovascular dysfunction and diminished vascular nitric
oxide (NO) production. We hypothesized that overexpression of endothelial NO synthase (…

Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique

…, GWA van Cappellen, J Bos, CJ Slager, DJ Duncker… - Blood, 2005 - ashpublications.org
The focal location of atherosclerosis in the vascular tree is correlated with local variations in
shear stress. We developed a method to induce defined variations in shear stress in a …

[PDF][PDF] Peripheral circulation

…, J Padilla, RJ Bache, D Merkus, DJ Duncker - Compr Physiol, 2012 - academia.edu
Blood flow (BF) increases with increasing exercise intensity in skeletal, respiratory, and
cardiac muscle. In humans during maximal exercise intensities, 85% to 90% of total cardiac …

Depression and coronary heart disease: 2018 position paper of the ESC working group on coronary pathophysiology and microcirculation

…, J Cubedo, M Dorobantu, DJ Duncker… - European heart …, 2020 - academic.oup.com
Major depression is a highly prevalent condition, affecting approximately 10% of the
population. 1 It is also a growing global problem, 2 and has been consistently associated with …

Sites of action of adenosine in interorgan preconditioning of the heart

…, H Ploeg, S Kazim, DJ Duncker - American Journal of …, 2002 - journals.physiology.org
The mechanism underlying interorgan preconditioning of the heart remains elusive, although
a role for adenosine and activation of a neurogenic pathway has been postulated. We …