Menstruation occurs at the end of a normal reproductive cycle in the human female, following
the fall in progesterone resulting from the demise of the corpus luteum. Current data …

Matrix metalloproteinases (MMP) are strongly implicated in menstruation. Messenger RNA
for proMMP-1 and -3 was detectable in normal cycle endometrium only peri-menstrually and …

Rheumatoid arthritis is a chronic destructive disease of joints, characterized by inflammation,
synovial hyperplasia, and abnormal cellular and humoral immune responses. Although …

Objective To examine by immunohistochemistry the relative distributions of 6 matrix
metalloproteinases (MMPs 1, 2, 3, 8, 9, and 13) and the 2 proinflammatory cytokines interleukin‐1β (…

cDNA microarray technology is used to profile complex diseases and discover novel
disease-related genes. In inflammatory disease such as rheumatoid arthritis, expression patterns of …

… Bromley M, Woolley DE: Histopathology of the rheumatoid lesion: identification of cell types
at sites of cartilage erosion. Arthritis Rheum 27:857-863, 1984 11. Uhlingcr E: Bone changes …

… Edited by DE Woolley, JM Evanson. Chichester, UK, John Wiley and Sons, 1980, pp 105-125 …
Woolley DE: Mast cells at sites of cartilage erosion in the rheumatoid joint. Ann Rheum Dis …

An improved immunohistochemical method has been used to assess neovascularization
within the vulnerable ‘shoulder’regions of atherosclerotic plaques from carotid arteries. A …

Objectives To examine the in situ distributions of vitamin D receptors (VDR) and matrix
metalloproteinases (MMPs) in osteoarthritic cartilage for comparison with non-arthritic, normal …

Statement of findings Mast cell (MC) activation in the rheumatoid lesion provides numerous
mediators that contribute to inflammatory and degradative processes, especially at sites of …