Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐and A‐dependent mechanisms in rats and mice

…, F Bautista, R Karanjia, C BarajasLopez… - The Journal of …, 2006 - Wiley Online Library
Proteases that are released during inflammation and injury cleave protease‐activated
receptor 2 (PAR 2 ) on primary afferent neurons to cause neurogenic inflammation and …

Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

AD Grant, GS Cottrell, S Amadesi… - The Journal of …, 2007 - Wiley Online Library
Exacerbated sensitivity to mechanical stimuli that are normally innocuous or mildly painful (mechanical
allodynia and hyperalgesia) occurs during inflammation and underlies painful …

Mast cell tryptase and proteinase‐activated receptor 2 induce hyperexcitability of guinea‐pig submucosal neurons

DE Reed, C BarajasLopez, G Cottrell… - The Journal of …, 2003 - Wiley Online Library
Mast cells that are in close proximity to autonomic and enteric nerves release several mediators
that cause neuronal hyperexcitability. This study examined whether mast cell tryptase …

ATP inhibits glutamate synaptic release by acting at P2Y receptors in pyramidal neurons of hippocampal slices

…, RD Andrew, C Barajas-López - Journal of Pharmacology …, 2000 - ASPET
It has been proposed that extracellular ATP inhibits synaptic release of glutamate from
hippocampal CA1 synapses after its catabolism to adenosine. We investigated the possibility that …

Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels

É Boué-Grabot, C Barajas-López, Y Chakfe… - Journal of …, 2003 - Soc Neuroscience
Fast chemical communications in the nervous system are mediated by several classes of
receptor channels believed to be independent functionally and physically. We show here that …

Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons

…, C Ibeakanma, C Barajas-Lopez… - American Journal …, 2010 - journals.physiology.org
This study examined whether bacterial cell products that might gain access to the intestinal
interstitium could activate mouse colonic nociceptive dorsal root ganglion (DRG) neurons …

Functional interactions between nicotinic and P2X channels in short‐term cultures of guinea‐pig submucosal neurons

C BarajasLópez, R Espinosa‐Luna… - The Journal of …, 1998 - Wiley Online Library
1 Functional interactions between nicotinic and P2X receptors in submucosal neurons were
investigated. Whole‐cell currents induced by ACh ( I ACh ) and ATP ( I ATP ) were blocked …

Interferon-α inhibits long-term potentiation and unmasks a long-term depression in the rat hippocampus

V Mendoza-Fernandez, RD Andrew, C Barajas-López - Brain research, 2000 - Elsevier
Interferons (IFN) appear to have various neuromodulatory actions. Here, we characterized the
actions of IFN-α on the electrophysiological properties of CA1 hippocampal neurons using …

Melatonin modulates cholinergic transmission by blocking nicotinic channels in the guinea-pig submucous plexus

C Barajas-López, AL Peres, R Espinosa-Luna… - European journal of …, 1996 - Elsevier
Melatonin, a hormone produced and released by the pineal gland, is also synthesized by cells
of the gastrointestinal wall, where it might be a local regulator of gut functions. In this study…

Pacemaker activity recorded in interstitial cells of Cajal of the gastrointestinal tract

C Barajas-Lopez, I Berezin… - American Journal of …, 1989 - journals.physiology.org
… the long axis of circular muscle cells (Barajas-Lopez and Huizinga, unpublished results), …
cells of this tissue is ~25 mm/s (Barajas-Lopez and Huizinga, unpublished results), which is …