Conformation of pleionomers of. alpha.-aminoisobutyric acid
…, P Grimaldi, F Lelj, V Pavone, C Pedone - …, 1985 - ACS Publications
The IR absorption and NMR analysis of the preferred conformation of monodisperse Z-(Aib)„-OtBu
(Z=(benzyloxy) carbonyl, OtBu= tert-butoxy, Aib=-aminoisobutyric acid;= 1-12) …
(Z=(benzyloxy) carbonyl, OtBu= tert-butoxy, Aib=-aminoisobutyric acid;= 1-12) …
Bioactive peptides: solid-state and solution conformation of cyclolinopeptide A
…, E Benedetti, V Pavone, C Pedone… - Journal of the …, 1989 - ACS Publications
The solid-state and solution conformational analysis of cyclolinopeptide A, a cyclic
nonapeptide isolated from linseed, is reported. The X-ray crystalstructure determinationof the …
nonapeptide isolated from linseed, is reported. The X-ray crystalstructure determinationof the …
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
…, S Pastorekova, C Pedone… - Proceedings of the …, 2009 - National Acad Sciences
Carbonic anhydrase (CA) IX is a plasma membrane-associated member of the α-CA enzyme
family, which is involved in solid tumor acidification. It is a marker of tumor hypoxia and a …
family, which is involved in solid tumor acidification. It is a marker of tumor hypoxia and a …
Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Hedgehog signalling is crucial for development and is deregulated in several tumours,
including medulloblastoma. Regulation of the transcriptional activity of Gli (glioma-associated …
including medulloblastoma. Regulation of the transcriptional activity of Gli (glioma-associated …
Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide
…, D Capasso, B Trimarco, C Pedone - Proceedings of the …, 2005 - National Acad Sciences
Modulating angiogenesis is an attractive goal because many pathological conditions depend
on the growth of new vessels. Angiogenesis is mainly regulated by the VEGF, a mitogen …
on the growth of new vessels. Angiogenesis is mainly regulated by the VEGF, a mitogen …
Bioactive peptides: X-ray and NMR conformational study of [Aib5, 6-D-Ala8] cyclolinopeptide A
The conformational analysis of [Aib5-6-o-Ala8] cyclolinopeptide A, in the solid state and
solution, has been carried out by X-ray diffraction and NMR spectroscopy. The structure of the …
solution, has been carried out by X-ray diffraction and NMR spectroscopy. The structure of the …
Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX
V Alterio, RM Vitale, SM Monti, C Pedone… - Journal of the …, 2006 - ACS Publications
The X-ray crystal structure of the fluorescent antitumor sulfonamide carbonic anhydrase (CA,
EC, 4.2.1.1) inhibitor (4-sulfamoylphenylethyl)thioureido fluorescein (1) in complex with the …
EC, 4.2.1.1) inhibitor (4-sulfamoylphenylethyl)thioureido fluorescein (1) in complex with the …
Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a d-lysine-based chiral PNA–DNA duplex
…, D Capasso, M Saviano, C Pedone - Proceedings of the …, 2003 - National Acad Sciences
Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate
backbone has been replaced by a pseudopeptide skeleton. They bind DNA and RNA with …
backbone has been replaced by a pseudopeptide skeleton. They bind DNA and RNA with …
Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies
G De Simone, A Di Fiore, V Menchise, C Pedone… - Bioorganic & medicinal …, 2005 - Elsevier
The antiepileptic drug zonisamide was considered to act as a weak inhibitor of the zinc enzyme
carbonic anhydrase (CA, EC 4.2.1.1) (with a K I of 4.3μM against the cytosolic isozyme II)…
carbonic anhydrase (CA, EC 4.2.1.1) (with a K I of 4.3μM against the cytosolic isozyme II)…
Selectively functionalized cyclodextrins and their metal complexes
F Bellia, D La Mendola, C Pedone… - Chemical Society …, 2009 - pubs.rsc.org
… Carlo Pedone Carlo Pedone obtained his Doctor of Chemistry degree cum laude in 1961.
He began his scientific career in the field of Macromolecular Chemistry under the guidance of …
He began his scientific career in the field of Macromolecular Chemistry under the guidance of …