Although homo-oligomerization has been reported for several G protein-coupled receptors,
this phenomenon was not studied at low concentrations of receptors. Furthermore, it is not …

… CD1 mice (25–30 g) used for turning behavior studies and male albino guinea pigs (300–350
g) used for brain membrane preparation for binding studies were obtained from Charles …

β-Arrestins (βarr) are multifunctional adaptor proteins that can act as scaffolds for G protein-coupled
receptor activation of mitogen-activated protein kinases (MAPK). Here, we identify …

G-protein-coupled receptors (GPCRs) are dynamically regulated by various mechanisms
that tune their response to external stimuli. Modulation of their plasma membrane density, via …

… Cells were incubated for 3 hr at 37C, and the medium was removed and replaced by the …
The oocytes were then incubated at 18C for 2–4 d. Electrophysiological measurements …

Arrestins are important proteins, which regulate the function of serpentine heptahelical receptors
and contribute to multiple signaling pathways downstream of receptors. The ubiquitous …

Two G protein-coupled neurotensin (NT) receptors, termed NTR1 and NTR2, have been
identified so far. In contrast to the NTR1, which has been extensively studied, little is known …

β-arrestins (β-arrs), two ubiquitous proteins involved in serpentine heptahelical receptor
regulation and signaling, form constitutive homo- and heterooligomers stabilized by inositol 1,2,3…

The neurotensin receptor 1 (NTR1) subtype belongs to the family of G protein-coupled
receptors and mediates most of the known effects of the neuropeptide including modulation of …

… C. Labbé-Jullié, unpublished observation.S. Barroso, unpublished observations. … After
homogenization by repeated passages through a syringe needle and centrifugation at 4 C for 30 …