Acute μ and κ opioids activate the ERK/MAPK phosphorylation cascade that represents an
integral part of the signaling pathway of growth factors in astrocytes. By this cross-talk, opioids …

… Barg, J., Belcheva, M., McHale, RJ, and Coscia, CJ Inhibition of 3Hthymidine incorporation
into DNA or fetal rat brain aggregates. In: JM van Ree, AH Mulder, VM Wiegant, and TB van …

We investigated the postnatal ontogeny of opioid receptors in rat brain under assay conditions
which, when combined with computerized analysis, effectively reflect the developmental …

… 106 Ignatova EG, Belcheva MM, Bohn LM, Neuman MC, Coscia CJ: Requirement of receptor
internalization for opioid stimulation of mitogen-activated protein kinase: Biochemical and …

Phosphorylation of the MAPK isoform ERK by G protein-coupled receptors involves multiple
signaling pathways. One of these pathways entails growth factor receptor transactivation …

Although it is well‐established that G protein‐coupled receptor signaling systems can
network with those of tyrosine kinase receptors by several mechanisms, the point(s) of …

GTP binding regulatory protein (G protein)‐coupled receptors can activate MAPK pathways
via G protein‐dependent and ‐independent mechanisms. However, the physiological …

Growth factors, hormones, and neurotransmitters have been implicated in the regulation of
stem cell fate. Since various neural precursors express functional neurotransmitter receptors, …

As reports on G protein‐coupled receptor signal transduction mechanisms continue to
emphasize potential differences in signaling due to relative receptor levels and cell type …

Opioid receptor signaling via EGF receptor (EGFR) transactivation and ERK/MAPK
phosphorylation initiates diverse cellular responses that are cell type-dependent. In astrocytes, …