Background Genetic studies have shown that C9orf72, SOD1, TARDBP and FUS are the most
common mutated genes in amyotrophic lateral sclerosis (ALS). Here, we performed a meta…

The physical and chemical properties of silver nanoparticles that are responsible for their
antimicrobial activities have been studied with spherical silver nanoparticles (average diameter …

Silver nanoparticles (nano-Ag) are potent and broad-spectrum antimicrobial agents. In this
study, spherical nano-Ag (average diameter = 9.3 nm) particles were synthesized using a …

… comes from the alcohol, which supports the ketone oxidation and benzylic C−H mechanism.
His report agrees with He’s simultaneous finding on benzylic C−H activation (Scheme 52). …

… The structural and functional similarity between a C-terminal motif in mammalian p62 and …
and LGG-1, the Atg8 homolog in C. elegans, and thus functions similarly to Atg19 and p62. …

… each recombinant protein at pH 7.5 and 16 C overnight, followed by complete digestion to
single … To our delight, we found that recombinant ALKBH5 (Figure S1C) can completely deme…

5-methylcytosine (5mC) in DNA plays an important role in gene expression, genomic
imprinting, and suppression of transposable elements. 5mC can be converted to 5-…

… (B) TLC confirmation of the origin of spot X from 5mC with a 14 C-labeled methyl group. (C)
HPLC detection of a new nucleoside generated from 5mC and 5hmC DNA substrates upon …

N 6 -methyladenosine (m 6 A) is the most prevalent internal (non-cap) modification present
in the messenger RNA of all higher eukaryotes 1 , 2 . Although essential to cell viability and …

… C=C double bonds (27). The intensity of this 3015 cm –1 mode is approximately proportional
to the number of C=C … six C=C bonds), eicosapentaenoic acid (EPA, with five C=C bonds), …