Rare and low-frequency coding variants alter human adult height

…, FW Asselbergs, PL Auer, B Balkau, B Banas… - Nature, 2017 - nature.com
Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

[HTML][HTML] Everolimus in patients with autosomal dominant polycystic kidney disease

…, C Sommerer, U Kunzendorf, B Banas… - … England Journal of …, 2010 - Mass Medical Soc
Background Autosomal dominant polycystic kidney disease (ADPKD) is a slowly progressive
hereditary disorder that usually leads to end-stage renal disease. Although the underlying …

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

…, A Secchi, K Crisalli, SM Kang, R Hilton, B Banas… - The Lancet, 2020 - thelancet.com
Background Use of cell-based medicinal products (CBMPs) represents a state-of-the-art
approach for reducing general immunosuppression in organ transplantation. We tested multiple …

Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial

…, H Wolters, T Rath, T Cingöz, U Benck, B Banas… - The Lancet, 2016 - thelancet.com
Background Standard practice for immunosuppressive therapy after renal transplantation is
quadruple therapy using antibody induction, low-dose tacrolimus, mycophenolate mofetil, …

After ten years of follow-up, no difference between supportive care plus immunosuppression and supportive care alone in IgA nephropathy

…, O Sarkar, M Stefanidou, H Pavenstädt, B Banas… - Kidney international, 2020 - Elsevier
The randomized, controlled STOP-IgAN trial in patients with IgA nephropathy (IgAN) and
substantial proteinuria showed no benefit of immunosuppression added on top of supportive …

Signaling danger: toll-like receptors and their potential roles in kidney disease

HJ Anders, B Banas, D Schlöndorff - Journal of the American …, 2004 - journals.lww.com
ABSTRACT. Toll-like receptors (TLR) are an emerging family of receptors that recognize
pathogen-associated molecular patterns and promote the activation of leukocytes and intrinsic …

The mesangial cell revisited: no cell is an island

D Schlo, B Banas - Journal of the American Society of …, 2009 - journals.lww.com
Mesangial cells and their matrix form the central stalk of the glomerulus and are part of a
functional unit interacting closely with endothelial cells and podocytes. Alterations in one cell …

Biomarker-guided intervention to prevent acute kidney injury after major surgery: the prospective randomized BigpAK study

…, F Zeman, C Gnewuch, BM Graf, W Gnann, B Banas… - 2018 - journals.lww.com
Objective: To determine the impact of renal biomarker–guided implementation of the Kidney
Disease Improving Global Outcomes (KDIGO) care bundle on the incidence of acute kidney …

TLR4 links podocytes with the innate immune system to mediate glomerular injury

MC Banas, B Banas, KL Hudkins… - Journal of the …, 2008 - journals.lww.com
Toll-like receptors (TLR) classically recognize pathogen-associated danger signals but are
also activated via endogenous ligands. For evaluation of their role in inflammatory kidney …

Kidney injury molecule‐1 and N‐acetyl‐ß‐d‐glucosaminidase in chronic heart failure: possible biomarkers of cardiorenal syndrome

…, C von Bary, D Endemann, B Banas… - European journal of …, 2011 - Wiley Online Library
Aims Patients with chronic heart failure are often characterized by impaired renal function,
also referred to as cardiorenal syndrome (CRS). The aim of this study was to assess whether …