User profiles for B. T. Chait
Brian ChaitCamille and Henry Dreyfus Professor, The Rockefeller University Verified email at rockefeller.edu Cited by 93979 |
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
…, D Loayza, SM Hooper, BT Chait… - Genes & …, 2004 - genesdev.cshlp.org
Human telomere length is controlled by a negative feedback loop based on the binding of
TRF1 to double-stranded telomeric DNA. The TRF1 complex recruits POT1, a single-stranded …
TRF1 to double-stranded telomeric DNA. The TRF1 complex recruits POT1, a single-stranded …
Virtual gating and nuclear transport: the hole picture
The eukaryotic nucleus is surrounded by a protective nuclear envelope, which is perforated
by trafficking machines termed nuclear pore complexes (NPCs). The NPCs are the sole …
by trafficking machines termed nuclear pore complexes (NPCs). The NPCs are the sole …
Analysis of phosphorylated proteins and peptides by mass spectrometry
DT McLachlin, BT Chait - Current opinion in chemical biology, 2001 - Elsevier
Phosphorylation on serine, threonine and tyrosine residues is an extremely important modulator
of protein function. Therefore, there is a great need for methods capable of accurately …
of protein function. Therefore, there is a great need for methods capable of accurately …
The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity
…, RA Pfuetzner, A Kuo, JM Gulbis, SL Cohen, BT Chait… - science, 1998 - science.org
The potassium channel from Streptomyces lividans is an integral membrane protein with
sequence similarity to all known K + channels, particularly in the pore region. X-ray analysis …
sequence similarity to all known K + channels, particularly in the pore region. X-ray analysis …
Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene
The gene product of the ob locus is important in the regulation of body weight. The ob product
was shown to be present as a 16-kilodalton protein in mouse and human plasma but was …
was shown to be present as a 16-kilodalton protein in mouse and human plasma but was …
Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers
…, M Karas, RC Beavis, BT Chait - Analytical chemistry, 1991 - ACS Publications
Analytical chemists and biochemists have long sought accurate, sensitive methods for
determining the molecu-lar masses of biopolymers such as proteins and carbohydrates. Tradi-…
determining the molecu-lar masses of biopolymers such as proteins and carbohydrates. Tradi-…
X-ray structure of a voltage-dependent K+ channel
Voltage-dependent K + channels are members of the family of voltage-dependent cation (K
+ , Na + and Ca 2+ ) channels that open and allow ion conduction in response to changes in …
+ , Na + and Ca 2+ ) channels that open and allow ion conduction in response to changes in …
X-ray structure of a ClC chloride channel at 3.0 Ĺ reveals the molecular basis of anion selectivity
The ClC chloride channels catalyse the selective flow of Cl - ions across cell membranes,
thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across …
thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across …
Accurate quantitation of protein expression and site-specific phosphorylation
A mass spectrometry-based method is described for simultaneous identification and
quantitation of individual proteins and for determining changes in the levels of modifications at …
quantitation of individual proteins and for determining changes in the levels of modifications at …
The yeast nuclear pore complex: composition, architecture, and transport mechanism
… We thank Julia Kipper, Rosemary Williams, Yongmin Oh, Dwayne Weber, and other members
of the Rout, Chait, and Aitchison laboratories, as well as Rick Wozniak and Christopher …
of the Rout, Chait, and Aitchison laboratories, as well as Rick Wozniak and Christopher …