Synthesis and biological evaluation of 2-styrylquinazolin-4 (3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization

JB Jiang, DP Hesson, BA Dusak… - Journal of medicinal …, 1990 - ACS Publications
A novel series of 2-styrylquinazolin-4 (3H)-ones which inhibited tubulin polymerization and
the growthof L1210 murine leukemiacells was discovered. Extensive structure-activity …

Activity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2′-fluoro-1, 1′-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium salt], against …

…, RJ Ardecky, GV Rao, DL Tippett, BA Dusak… - Cancer research, 1985 - AACR
A novel, substituted 4-quinolinecarboxylic acid (NSC 339768) demonstrated antitumor
activity against L1210 leukemia and B16 melanoma in the National Cancer Institute's …

Effects of modulation of basic fibroblast growth factor on tumor growth in vivo

JL Gross, WF Herblin, BA Dusak… - JNCI: Journal of the …, 1993 - academic.oup.com
Background Recombinant human basic fibroblast growth factor (rHu-bFGF) is known to
stimulate proliferation in some tumor cells and to modulate tumor vascularization. Purpose The …

Cytotoxicity of synthetic racemic ptilocaulin: A novel cyclic guanidine

…, BB Snider, FW Hobbs, PN Confalone, BA Dusak - Investigational new …, 1989 - Springer
(+)-Ptilocaulin, a novel cyclic guanidine extracted from the Caribbean sponge Ptilocaulis aff.
P. Spiculifer, is reported to have broad spectrum antimicrobial activity in vitro as well as in …

Once-daily quadruple-drug therapy with adefovir dipivoxil, lamivudine, didanosine, and efavirenz in treatment-naïve human immunodeficiency virus type 1–infected …

…, KE Squires, SD Goodwin, BA Dusak… - The Journal of …, 2002 - academic.oup.com
A 48-week open-label study of 11 antiretroviral-naive, human immunodeficiency virus type
1 (HIV-1)–infected adults evaluated once-daily treatment with adefovir dipivoxil, lamivudine, …

[PDF][PDF] Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound …

BJ Aungst, JA Blake, NJ Rogers, BA Dusak - Journal of Pharmacology and …, 1990 - Citeseer
ABSTRACT ABBREVIATIONS: HPLC, High-performance liquid chromatography; Vd, volume
of distribution at steady state; CIS, systemic clearance; MAT,, mean residence time in …

B lymphocyte expression of a recognition locus for human monocytes and macrophages

D Guerry IV, BA Dusak, AD Schreiber… - The Journal of …, 1978 - journals.aai.org
Monocyte and macrophage interactions with other cell types are critical to certain immune
responses. Such interactions usually require close physical contact between mononuclear …

[CITATION][C] DuP-785, 6-fluoro-2-(2-fluoro-1, 1′-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium salt, a novel antineoplastic agent: Activity against …

…, GV Rao, RL Ruben, DL Tippett, BA Dusak… - Proc. AACR, 1985 - hero.epa.gov
DUP-785 (6-FLUORO-2-(2'FLUORO-1,1'BIPHENYL-4-YL)-3-METHYL-4-QUINOLINECARBOXYLIC
ACID SODIUM-SALT), A NOVEL ANTINEOPLASTIC AGENT - ACTIVITY AGAINST …

[CITATION][C] Modulation of solid tumor growth in vivo by bFGF

JL Gross, WF Herblin, BA Dusak, P Czerniak… - Proc Am Assoc Cancer Res, 1990

[CITATION][C] Dexter, DL; Kang, GJ; Harmel E. Synthesis and Biological Evaluation of 2-Styrylquinazolin-4 (3H)-ones, a New Class of Antimitotic Anticancer Agents …

JB Jiang, DP Hesson, BA Dusak - J. Med. Chem, 1990