User profiles for Arvind Mathur

AK Mathur

Assistant Professor, Internal Medicine, Western University of Health Sciences
Verified email at llu.edu
Cited by 288

Methods for synthesis of hydrogel networks: A review

AM Mathur, SK Moorjani… - Journal of Macromolecular …, 1996 - Taylor & Francis
Hydrogels are macromolecular networks that swell, but do not dissolve, in water. The ability
of hydrogels to absorb water arises from hydrophilic functional groups attached to the …

Delayed paracentesis is associated with increased in-hospital mortality in patients with spontaneous bacterial peritonitis

JJ Kim, MM Tsukamoto, AK Mathur… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: Spontaneous bacterial peritonitis (SBP) is associated with high mortality.
Early paracentesis (EP) is essential for rapid diagnosis and optimal treatment. The aim of the …

Utilization of C(sp3)‐Carboxylic Acids and Their Redox‐Active Esters in Decarboxylative Carbon−Carbon Bond Formation

…, A Silamkoti, NA Meanwell, A Mathur… - Advanced Synthesis …, 2021 - Wiley Online Library
Over the last several years, radical‐mediated decarboxylative cross‐coupling reactions
employing alkyl carboxylic acids have emerged as a powerful tool for the regiospecific …

Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2, 4-dioxo-1, 2-dihydroquinazolin-3 (4 H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2, 3, 4, 9-tetrahydro-1 …

…, CY Chang, R Rampulla, A Mathur… - Journal of medicinal …, 2016 - ACS Publications
Bruton's tyrosine kinase (BTK), a nonreceptor tyrosine kinase, is a member of the Tec family
of kinases. BTK plays an essential role in B cell receptor (BCR)-mediated signaling as well …

Discovery and Preclinical Studies of (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an In …

…, JC Barrish, SH Kim, K Leavitt, A Mathur… - Journal of medicinal …, 2006 - ACS Publications
A series of substituted 4-(4-fluoro-1H-indol-5-yloxy)pyrrolo[2,1-f][1,2,4]triazine-based
inhibitors of vascular endothelial growth factor receptor-2 kinase is reported. Structure−activity …

Discovery of milvexian, a high-affinity, orally bioavailable inhibitor of factor XIa in clinical studies for antithrombotic therapy

…, DJP Pinto, Y Wang, Y Zhu, A Mathur… - Journal of medicinal …, 2021 - ACS Publications
Factor XIa (FXIa) is an enzyme in the coagulation cascade thought to amplify thrombin
generation but has a limited role in hemostasis. From preclinical models and human genetics, an …

A new conceptual framework for maternal morbidity

…, I Lange, LA Magee, A Mathur… - … of Gynecology & …, 2018 - Wiley Online Library
Background Globally, there is greater awareness of the plight of women who have complications
associated with pregnancy or childbirth and who may continue to experience long‐term …

Synthesis of cyclobutane-fused tetracyclic scaffolds via visible-light photocatalysis for building molecular complexity

…, AK Gupta, NA Meanwell, A Mathur… - Journal of the …, 2020 - ACS Publications
We describe the synthesis through visible-light photocatalysis of novel functionalized
tetracyclic scaffolds that incorporate a fused azabicyclo[3.2.0]heptan-2-one motif, which are …

Polymeric emulsifiers based on reversible formation of hydrophobic units

AM Mathur, B Drescher, AB Scranton, J Klier - Nature, 1998 - nature.com
Emulsions consist of mixtures of immiscible liquids where one liquid is finely dispersed within
the continuous phase of another. They are generally not thermodynamically stable: the …

Discovery of branebrutinib (BMS-986195): a strategy for identifying a highly potent and selective covalent inhibitor providing rapid in vivo inactivation of Bruton's …

…, R Rampulla, A Allentoff, MA Wallace, A Mathur… - 2019 - ACS Publications
Bruton’s tyrosine kinase (BTK), a non-receptor tyrosine kinase, is a member of the Tec family
of kinases and is essential for B cell receptor (BCR) mediated signaling. BTK also plays a …