User profiles for Anup Patnaik
 | Anup PatnaikCenturion University Verified email at cutm.ac.in Cited by 5 |
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors
…, JE Grob, A McRiner, MR Pancost, A Patnaik… - Bioorganic & medicinal …, 2011 - Elsevier
Herein we report the discovery of a family of novel yet simple, amino-acid derived class I
HDAC inhibitors that demonstrate isoform selectivity via access to the internal acetate release …
HDAC inhibitors that demonstrate isoform selectivity via access to the internal acetate release …
Identification of orally available naphthyridine protein kinase D inhibitors
…, N Pagratis, M Pancost, A Patnaik… - Journal of medicinal …, 2010 - ACS Publications
A novel 2,6-naphthyridine was identified by high throughput screen (HTS) as a dual protein
kinase C/D (PKC/PKD) inhibitor. PKD inhibition in the heart was proposed as a potential …
kinase C/D (PKC/PKD) inhibitor. PKD inhibition in the heart was proposed as a potential …
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC
…, DT Parker, Y Peng, M Dobler, A Patnaik… - Journal of medicinal …, 2017 - ACS Publications
Over the past several decades, the frequency of antibacterial resistance in hospitals,
including multidrug resistance (MDR) and its association with serious infectious diseases, has …
including multidrug resistance (MDR) and its association with serious infectious diseases, has …
Optical and electronic properties of some semiconductors from energy gaps
SK Tripathy, A Pattanaik - Optical Materials, 2016 - Elsevier
II-VI and III-V tetrahedral semiconductors have significant potential for novel optoelectronic
applications. In the present work, some of the optical and electronic properties of these …
applications. In the present work, some of the optical and electronic properties of these …
2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication
…, A Honda, S Sokup, S Karur, S Britt, A Patnaik… - Bioorganic & Medicinal …, 2014 - Elsevier
Synthesis and SAR of 2-alkyloxazoles as class III phosphatidylinositol-4-kinase beta (PI4KIIIβ)
inhibitors is described. These compounds demonstrate that inhibition of PI4KIIIβ leads to …
inhibitors is described. These compounds demonstrate that inhibition of PI4KIIIβ leads to …
Discovery of a novel indole pharmacophore for the irreversible inhibition of myeloperoxidase (MPO)
A Patnaik, L Axford, L Deng, E Cohick, X Ren… - Bioorganic & Medicinal …, 2020 - Elsevier
Myeloperoxidase (MPO) activity and subsequent generation of hypochlorous acid has been
associated with the killing of host-invading microorganisms (eg bacteria, viruses, and fungi). …
associated with the killing of host-invading microorganisms (eg bacteria, viruses, and fungi). …
Intelligent Decision Support System in Healthcare using Machine Learning Models
A Patnaik - Recent Patents on Engineering, 2024 - ingentaconnect.com
Background: The use of intelligent decision support systems (IDSS) is widespread in the
healthcare industry, particularly for real-time data, client and family history datasets, and …
healthcare industry, particularly for real-time data, client and family history datasets, and …
Discovery of a novel, highly potent and orally bioavailable pyrrolidinone indole series of irreversible Myeloperoxidase (MPO) inhibitors
…, L Deng, A Reynolds, J Mao, Q Liu, A Patnaik… - Biochemical …, 2023 - Elsevier
Myeloperoxidase (MPO) is a heme-containing peroxidase from phagocytic cells, which plays
an important role in the innate immune response. The primary anti-microbial function of …
an important role in the innate immune response. The primary anti-microbial function of …
Discovery of 1-((6-aminopyridin-3-yl) methyl)-3-(4-bromophenyl) urea as a potent, irreversible myeloperoxidase inhibitor
…, L Deng, A Reynolds, X Ren, L Axford, A Patnaik… - … of Pharmacology and …, 2018 - ASPET
Myeloperoxidase (MPO) is a leukocyte-derived redox enzyme that has been linked to oxidative
stress and damage in many inflammatory states, including cardiovascular disease. We …
stress and damage in many inflammatory states, including cardiovascular disease. We …
Blockchain based holistic trust management protocol for ubiquitous and pervasive IoT network
The new emerging blockchain (BC) technology integrated with the IoT ecosystem
revolutionised the IoT world. Classic BC with bitcoin method was realised as very expensive …
revolutionised the IoT world. Classic BC with bitcoin method was realised as very expensive …