User profiles for Antal Tapodi
 | Tapodi AntalPTE ÁOK Verified email at aok.pte.hu Cited by 614 |
[HTML][HTML] Pivotal role of Akt activation in mitochondrial protection and cell survival by poly (ADP-ribose) polymerase-1 inhibition in oxidative stress
According to the classical view, the cytoprotective effect of inhibitors of poly(ADP-ribose)polymerase
(PARP) in oxidative stress was based on the prevention of NAD + and ATP depletion…
(PARP) in oxidative stress was based on the prevention of NAD + and ATP depletion…
Regulation of MKP-1 expression and MAPK activation by PARP-1 in oxidative stress: a new mechanism for the cytoplasmic effect of PARP-1 activation
Previously, it was suggested that the release of nuclearly formed ADP-ribose polymers or
ADP-ribosylated proteins could be responsible for the cytosolic and mitochondrial effects of …
ADP-ribosylated proteins could be responsible for the cytosolic and mitochondrial effects of …
[HTML][HTML] PARP inhibition induces Akt-mediated cytoprotective effects through the formation of a mitochondria-targeted phospho-ATM-NEMO-Akt-mTOR signalosome
Purpose The cytoprotective effect of poly(ADP-ribose) polymerase 1 (PARP1) inhibition is
well documented in various cell types subjected to oxidative stress. Previously, we have …
well documented in various cell types subjected to oxidative stress. Previously, we have …
Concentration dependent mitochondrial effect of amiodarone
Although, the antiarrhythmic effect of amiodarone is well characterized, its effect on post-ischemic
heart and cardiomyocytes, as well as the mechanism of its toxicity on extracardiac …
heart and cardiomyocytes, as well as the mechanism of its toxicity on extracardiac …
A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death
In ischemia–reperfusion injuries, elevated calcium and reactive oxygen species (ROS)
induce mitochondrial permeability transition (mPT), which plays a pivotal role in mediating …
induce mitochondrial permeability transition (mPT), which plays a pivotal role in mediating …
Protective effect of amiodarone but not N-desethylamiodarone on postischemic hearts through the inhibition of mitochondrial permeability transition
Amiodarone is a widely used and potent antiarrhythmic agent that is metabolized to
desethylamiodarone. Both amiodarone and its metabolite possess antiarrhythmic effect, and both …
desethylamiodarone. Both amiodarone and its metabolite possess antiarrhythmic effect, and both …
[HTML][HTML] BFSP1 C-terminal domains released by post-translational processing events can alter significantly the calcium regulation of AQP0 water permeability
BFSP1 (beaded filament structural protein 1, filensin) is a cytoskeletal protein expressed in
the eye lens. It binds AQP0 in vitro and its C-terminal sequences have been suggested to …
the eye lens. It binds AQP0 in vitro and its C-terminal sequences have been suggested to …
Prevalent role of Akt and ERK activation in cardioprotective effect of Ca2+ channel- and beta-adrenergic receptor blockers
We studied cardioprotective as well as Akt and extracellular signal-activated kinase (ERK)
activating effect of a Ca 2+ antagonist and a beta-adrenergic receptor blocker during ischemia…
activating effect of a Ca 2+ antagonist and a beta-adrenergic receptor blocker during ischemia…
[HTML][HTML] Desethylamiodarone—A metabolite of amiodarone—Induces apoptosis on T24 human bladder cancer cells via multiple pathways
Bladder cancer (BC) is a common malignancy of the urinary tract that has a higher frequency
in men than in women. Cytostatic resistance and metastasis formation are significant risk …
in men than in women. Cytostatic resistance and metastasis formation are significant risk …
[HTML][HTML] Studies on a widely-recognized snail model species (Lymnaea stagnalis) provide further evidence that vertebrate steroids do not have a hormonal role in the …
Experiments were carried out to determine whether, as with other mollusks that have been
studied, the snail, Lymnaea stagnalis, can absorb, esterify and store vertebrate steroids that …
studied, the snail, Lymnaea stagnalis, can absorb, esterify and store vertebrate steroids that …