Ischemia-induced shift of inhibitory and excitatory amino acids from intra-to extracellular compartments

H Hagberg, A Lehmann, M Sandberg… - Journal of Cerebral …, 1985 - journals.sagepub.com
Brain ischemia was induced for 10 or 30 min by clamping the common carotid arteries in
rabbits whose vertebral arteries had previously been electrocauterized. EEG and tissue content …

Control of transient lower esophageal sphincter relaxations and reflux by the GABAB agonist baclofen in normal subjects

I Lidums, A Lehmann, H Checklin, J Dent, RH Holloway - Gastroenterology, 2000 - Elsevier
Background & Aims: Transient lower esophageal sphincter (LES) relaxations are the major
mechanism of gastroesophageal reflux in normal subjects and in most patients with reflux …

The role of gastric motility in the control of food intake

…, S Verschueren, A Lehmann… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 880–894 Summary Background From a classical point of
view, gastric motility acts to clear the stomach between meals, whereas postprandial motility …

Effects of In Vivo Administration of Kainic Acid on the Extracellular Amino Acid Pool in the Rabbit Hippocampus

A Lehmann, H Isacsson… - Journal of …, 1983 - Wiley Online Library
The effect of local administration of kainic acid in the rabbit hippocampus was studied; the
hippocampus was perfused continuously in the freely moving animal with an implanted 0.3‐…

Intestinal SGLT1 in metabolic health and disease

A Lehmann, PJ Hornby - American Journal of Physiology …, 2016 - journals.physiology.org
The Na + -glucose cotransporter 1 (SGLT1/SLC5A1) is predominantly expressed in the
small intestine. It transports glucose and galactose across the apical membrane in a process …

The anticonvulsant gabapentin (Neurontin) does not act through γ-aminobutyric acid-B receptors

…, B Abrahamsen, JP Mattsson, A Lehmann… - Molecular …, 2002 - ASPET
The actions of the anticonvulsant gabapentin [1-(aminomethyl)cyclohexaneacetic acid,
Neurontin] have been somewhat enigmatic until recently, when it was claimed to be a γ-…

Effects of GABA agonists on body temperature regulation in GABAB(1)−/− mice

…, S Erickson, T Johansson, A Lehmann… - British journal of …, 2003 - Wiley Online Library
Activation of GABA B receptors evokes hypothermia in wildtype (GABA B(1) +/+ ) but not in
GABA B receptor knockout (GABA B(1) −/− ) mice. The aim of the present study was to …

The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection

P Andiné, A Lehmann, K Ellrén, E Wennberg… - Neuroscience …, 1988 - Elsevier
The neuroprotective effect of kynurenic acid, an unspecific antagonist of excitatory amino
acid receptors, was evaluated in a model of hypoxic-ischemia in neonatal rats. One-week-old …

Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia

…, A Walentinsson, G Davidson, L Agréus, A Lehmann… - Gut, 2009 - gut.bmj.com
Background and objectives: Gastro-oesophageal reflux disease (GORD) is a common
gastrointestinal disorder with a genetic component. Our aim was to identify genetic factors …

Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor

…, P Wellendorph, NHP Larsson, A Lehmann… - Journal of pharmacology …, 2013 - ASPET
The GPRC6A receptor is a recently “deorphanized” class CG protein–coupled receptor. We
and others have shown that this receptor is coactivated by basic l-α-amino acids and …