PURPOSE To provide real-world evidence on risks and outcomes of breakthrough COVID-19
infections in vaccinated patients with cancer using the largest national cohort of COVID-19 …

Coronary artery disease, leading to myocardial infarction and ischaemia, affects millions of
persons and is one of the leading causes of morbidity and mortality worldwide. Invasive …

Pseudoephedrine hydrochloride was used as a model drug to prepare direct compression
sustained release tablets with ethylcellulose (EC). Initially, different viscosity grades of EC …

Itaconate is produced from the mitochondrial TCA cycle enzyme aconitase decarboxylase (encoded
by immune responsive gene1; Irg1) that exerts immunomodulatory function in …

Objectives The purpose of this study was to determine the level of heterogeneity in high
grade serous ovarian cancer (HGSOC) by analyzing RNA expression in single epithelial and …

Curative responses in the treatment of multiple myeloma (MM) are limited by the emergence
of therapeutic resistance. To address this problem, we set out to identify druggable …

We used single cell RNA-Seq to examine molecular heterogeneity in multiple myeloma (MM)
in 597 CD138 positive cells from bone marrow aspirates of 15 patients at different stages of …

KLD-12 (KLD) is a 12-residue self-assembling peptide that can adopt nano-structures and
is known for its tissue-engineering properties. Our objective was to introduce antimicrobial …

Multiple myeloma (MM) is characterized by significant genetic diversity at subclonal levels
that have a defining role in the heterogeneity of tumor progression, clinical aggressiveness …

The FDA approved lenvatinib (Lenvima, Eisai Inc.) for the treatment of patients with locally
recurrent or metastatic, progressive, radioactive iodine-refractory (RAI-refractory) differentiated …