User profiles for Alexandros G Kokkosis
 | Alexandros G. KokkosisPostdoctoral Fellow, Velocigene-Human Systems Group, Regeneron Pharmaceuticals Verified email at regeneron.com Cited by 369 |
Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment
ZI Linardaki, MG Orkoula, AG Kokkosis… - Food and Chemical …, 2013 - Elsevier
In the present study, the possible reversal effects of saffron against established aluminum (Al)-toxicity
in adult mice, were investigated. Control, Al-treated (50mg AlCl 3 /kg/day diluted in …
in adult mice, were investigated. Control, Al-treated (50mg AlCl 3 /kg/day diluted in …
Chronic stress disrupts the homeostasis and progeny progression of oligodendroglial lineage cells, associating immune oligodendrocytes with prefrontal cortex …
AG Kokkosis, MM Madeira, MR Mullahy… - Molecular …, 2022 - nature.com
Major depressive disorder (MDD) is a chronic debilitating illness affecting yearly 300 million
people worldwide. Oligodendrocyte-lineage cells have emerged as important …
people worldwide. Oligodendrocyte-lineage cells have emerged as important …
[HTML][HTML] Non-canonical Wnt signaling regulates neural stem cell quiescence during homeostasis and after demyelination
Adult neural stem cells (NSCs) reside in a specialized microenvironment, the subventricular
zone (SVZ), which provides them with unique signaling cues to control their basic properties …
zone (SVZ), which provides them with unique signaling cues to control their basic properties …
Neuroimmune mechanisms and sex/gender-dependent effects in the pathophysiology of mental disorders
AG Kokkosis, SE Tsirka - Journal of Pharmacology and Experimental …, 2020 - ASPET
Innate and adaptive immune mechanisms have emerged as critical regulators of CNS
homeostasis and mental health. A plethora of immunologic factors have been reported to interact …
homeostasis and mental health. A plethora of immunologic factors have been reported to interact …
Lead-induced effects on learning/memory and fear/anxiety are correlated with disturbances in specific cholinesterase isoform activity and redox imbalance in adult …
AV Ferlemi, D Avgoustatos, AG Kokkosis… - Physiology & …, 2014 - Elsevier
The aim of the present study was to investigate whether the underlying mechanism of lead (Pb)-induced
effects on learning/memory and fear/anxiety behavior involves changes either …
effects on learning/memory and fear/anxiety behavior involves changes either …
Chronic psychosocial stress triggers microglial‐/macrophage‐induced inflammatory responses leading to neuronal dysfunction and depressive‐related behavior
Chronic environmental stress and traumatic social experiences induce maladaptive behavioral
changes and is a risk factor for major depressive disorder (MDD) and various anxiety‐…
changes and is a risk factor for major depressive disorder (MDD) and various anxiety‐…
[PDF][PDF] MOLECULAR AND BIOCHEMICAL MECHANISMS IN STREPTOZOTOCIN-INDUCED DIABETES AND ASSOCIATED BEHAVIORAL INDICES
AG KOKKOSIS - Citeseer
Diabetic encephalopathy, characterized by impaired cognitive function may involve
neuronal dysfunction and neurochemical abnormalities. Here we investigated the effects of …
neuronal dysfunction and neurochemical abnormalities. Here we investigated the effects of …
Chronic Stress Induces Microglial-Mediated Inflammatory Responses and Compromises the Oligodendroglial & Neuronal Homeostases Leading to Depression
AG Kokkosis - 2021 - search.proquest.com
… Stony Brook University August 2021 ii Stony Brook University The Graduate School
Alexandros G. Kokkosis We, the dissertation committee for the above candidate for the Doctor of …
Alexandros G. Kokkosis We, the dissertation committee for the above candidate for the Doctor of …
Immune Phenotypes of Oligodendroglial‐Lineage Cells in MDD and in Response to Chronic Stress‐Induced Microglial Inflammation
Background Major Depressive Disorder (MDD) is a complex and heterogenous psychiatric
disorder affecting more than 300 million people worldwide. Though the mechanisms …
disorder affecting more than 300 million people worldwide. Though the mechanisms …
Neuroimmune mechanisms and sexual dimorphism in the pathophysiology of mental disorders
AG Kokkosis, SE Tsirka - Journal of Pharmacology and Experimental …, 2020 - ASPET
Innate and adaptive immune mechanisms have emerged as critical regulators of CNS
homeostasis and mental health. A plethora of immunological factors have been reported to …
homeostasis and mental health. A plethora of immunological factors have been reported to …