User profiles for Abhay H. Pande
Dr. Abhay H. PandeProfessor, Department of Biotechnology,National Institute of Pharmaceutical Education and Verified email at niper.ac.in Cited by 1251 |
[HTML][HTML] Toward understanding the catalytic mechanism of human paraoxonase 1: site-specific mutagenesis at position 192
Human paraoxonase 1 (h-PON1) is a serum enzyme that can hydrolyze a variety of substrates.
The enzyme exhibits anti-inflammatory, anti-oxidative, anti-atherogenic, anti-diabetic, anti-…
The enzyme exhibits anti-inflammatory, anti-oxidative, anti-atherogenic, anti-diabetic, anti-…
Conformational instability of the cholera toxin A1 polypeptide
AH Pande, P Scaglione, M Taylor, KN Nemec… - Journal of molecular …, 2007 - Elsevier
… Author links open overlay panel Abhay H. Pande 1 2 1 , Patricia Scaglione 1 , Michael Taylor
1 , Kathleen N. Nemec 1 , Summer Tuthill 1 , David Moe 1 1 , Randall K. Holmes 3 , Suren A…
1 , Kathleen N. Nemec 1 , Summer Tuthill 1 , David Moe 1 1 , Randall K. Holmes 3 , Suren A…
Therapeutic potential of ApoE-mimetic peptides in CNS disorders: Current perspective
The prevalence and burden of CNS disorders are increasing significantly due to the increase
in life span and population. The contemporary need in CNS drug discovery is to develop …
in life span and population. The contemporary need in CNS drug discovery is to develop …
Polyspecificity-An emerging trend in the development of clinical antibodies
The essence of the growth and development of therapeutic conventional monoclonal antibodies
(MAbs) for the treatment of various disorders is the aptitude of MAbs to precisely bind a …
(MAbs) for the treatment of various disorders is the aptitude of MAbs to precisely bind a …
Immunomodulatory potential of apolipoproteins and their mimetic peptides in asthma: Current perspective
Asthma prevailed as a common inflammatory disease affecting mainly the lower respiratory
tract, with notable inflammation in the upper airways leading to significant morbidity and …
tract, with notable inflammation in the upper airways leading to significant morbidity and …
[PDF][PDF] Membrane fluidity is a key modulator of membrane binding, insertion, and activity of 5-lipoxygenase
AH Pande, S Qin, SA Tatulian - Biophysical journal, 2005 - cell.com
Mammalian 5-lipoxygenase (5-LO) catalyzes conversion of arachidonic acid to leukotrienes,
potent mediators of inflammation and allergy. Upon cell stimulation, 5-LO selectively binds …
potent mediators of inflammation and allergy. Upon cell stimulation, 5-LO selectively binds …
HDL, ApoA-I and ApoE-mimetic peptides: potential broad spectrum agent for clinical use?
Peptides mimicking the biological properties of apolipoproteins have shown beneficial
properties against a variety of diseases and have emerged as a potential candidate for their …
properties against a variety of diseases and have emerged as a potential candidate for their …
The pertussis toxin S1 subunit is a thermally unstable protein susceptible to degradation by the 20S proteasome
AH Pande, D Moe, M Jamnadas, SA Tatulian… - Biochemistry, 2006 - ACS Publications
Pertussis toxin (PT) is an AB-type protein toxin that consists of a catalytic A subunit (PT S1)
and an oligomeric, cell-binding B subunit. It belongs to a subset of AB toxins that move from …
and an oligomeric, cell-binding B subunit. It belongs to a subset of AB toxins that move from …
Polyvalency: an emerging trend in the development of clinical antibodies
Medicine has benefited greatly from the development of monoclonal antibody (mAb) technology.
First-generation mAbs have seen significant success in the treatment of major diseases, …
First-generation mAbs have seen significant success in the treatment of major diseases, …
Stabilization of the tertiary structure of the cholera toxin A1 subunit inhibits toxin dislocation and cellular intoxication
S Massey, T Banerjee, AH Pande, M Taylor… - Journal of molecular …, 2009 - Elsevier
Cholera toxin (CT) moves from the cell surface to the endoplasmic reticulum (ER) by retrograde
vesicular transport. The catalytic subunit of CT (CTA1) then crosses the ER membrane …
vesicular transport. The catalytic subunit of CT (CTA1) then crosses the ER membrane …